Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 1/20 | 0.31 |
| ▸ | CA6 | P23280 | 1/20 | 0.31 |
| ▸ | CA5A | P35218 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.31 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.31 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15120297 | 0.75 | KDM4E (0.44) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL7452989 | 0.70 | ENPP2 (0.39) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL2238608 | 0.69 | — | — | |
| SCHEMBL154802 | 0.69 | CA2 (0.42) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL9523 | 0.69 | HDAC1 (0.38) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL1427905 | 0.69 | ENPP2 (0.42) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL4556016 | 0.69 | ENPP2 (0.33) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL16361627 | 0.69 | ENPP2 (0.33) | CA4CA6CA5ACA7ENPP2 | |
| SCHEMBL21469007 | 0.69 | HDAC8 (0.36) | CA4CA6CA5ACA7ENPP2 | |
| Hydrochloric Acid SCHEMBL29955269 | 0.67 | HDAC1 (0.37) | CA4CA6CA5ACA7ENPP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012127212-A1 | IMIDAZO [1, 2 - B] PYRIDAZINE DERIVATIVES AS CDPK1 INHIBITORS | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2012-09-27 | — | — | WO | disclosed |
| WO-2011101640-A1 | FUSED HETEROCYCLIC COMPOUNDS FOR USE IN THE TREATMENT OF MALARIA | MEDICAL RESEARCH COUNCIL TECHNOLOGY (GB) | 2011-08-25 | — | — | WO | disclosed |