Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | CRHR1 | P34998 | 2/20 | 0.34 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | MITF | O75030 | 1/20 | 0.32 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2238261 | 0.74 | MEN1 (0.41) | MEN1KMT2ALMNAALDH1A1TSHR | |
| SCHEMBL1250322 | 0.72 | CA1 (0.43) | MEN1KMT2ACA1CA2KDM4E | |
| SCHEMBL30837586 | 0.72 | CA1 (0.43) | MEN1KMT2ACA1CA2KDM4E | |
| SCHEMBL17221363 | 0.69 | MEN1 (0.37) | MEN1KMT2ATSHRCRHR1NUDT1 | |
| SCHEMBL25111458 | 0.68 | CA1 (0.40) | MEN1KMT2ACA1CA2KDM4E | |
| SCHEMBL12037494 | 0.68 | KDM4E (0.43) | MEN1KMT2ACA1CA2KDM4E | |
| SCHEMBL3615606 | 0.68 | KDM4E (0.48) | CA1CA2KDM4ELMNAGAA | |
| SCHEMBL2430945 | 0.68 | NQO2 (0.42) | MEN1KMT2ACA1CA2KDM4E | |
| SCHEMBL11190041 | 0.67 | MEN1 (0.42) | MEN1KMT2ALMNAGAATSHR | |
| SCHEMBL11514316 | 0.67 | MEN1 (0.57) | MEN1KMT2AGAATSHRNUDT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 35 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10675285-B2 | Inhibitors of hemeprotein-catalyzed lipid peroxidation | VANDERBILT UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| US-10675285-B2 | Inhibitors of hemeprotein-catalyzed lipid peroxidation | VANDERBILT UNIVERSITY (US) | 2020-06-09 | — | — | US | disclosed |
| EP-2536690-B1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | UNIV ARIZONA (US) | 2018-08-08 | — | — | EP | disclosed |
| EP-2536690-B1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | UNIV ARIZONA (US) | 2018-08-08 | — | — | EP | disclosed |
| US-9545385-B2 | Inhibitors of hemeprotein-catalyzed lipid peroxidation | VANDERBILT UNIVERSITY (US) | 2017-01-17 | — | — | US | disclosed |
| US-9545385-B2 | Inhibitors of hemeprotein-catalyzed lipid peroxidation | VANDERBILT UNIVERSITY (US) | 2017-01-17 | — | — | US | disclosed |
| US-9545385-B2 | Inhibitors of hemeprotein-catalyzed lipid peroxidation | VANDERBILT UNIVERSITY (US) | 2017-01-17 | — | — | US | disclosed |
| US-20160067256-A1 | Inhibitors of Hemeprotein-Catalyzed Lipid Peroxidation | VANDERBILT UNIVERSITY | 2016-03-10 | — | — | US | disclosed |
| US-20160067256-A1 | Inhibitors of Hemeprotein-Catalyzed Lipid Peroxidation | VANDERBILT UNIVERSITY | 2016-03-10 | — | — | US | disclosed |
| US-20160067256-A1 | Inhibitors of Hemeprotein-Catalyzed Lipid Peroxidation | VANDERBILT UNIVERSITY | 2016-03-10 | — | — | US | disclosed |
| US-8367669-B2 | inhibiting heme-induced lipid peroxidation; preventing isoprostane-mediated tissue damage | VANDERBILT UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367669-B2 | inhibiting heme-induced lipid peroxidation; preventing isoprostane-mediated tissue damage | VANDERBILT UNIVERSITY (US) | 2013-02-05 | — | — | US | disclosed |
| EP-2536690-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | Arizona Board Of Regents (US) | 2012-12-26 | — | — | EP | disclosed |
| WO-2011103536-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | ARIZONA BOARD OF REGENTS (US) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011103536-A1 | MULTIFUNCTIONAL RADICAL QUENCHERS AND THEIR USE | ARIZONA BOARD OF REGENTS (US) | 2011-08-25 | — | — | WO | disclosed |
| US-20080227776-A1 | INHIBITORS OF HEMEPROTEIN-CATALYZED LIPID PEROXIDATION | VANDERBILT UNIVERSITY | 2008-09-18 | — | — | US | disclosed |
| US-20080227776-A1 | INHIBITORS OF HEMEPROTEIN-CATALYZED LIPID PEROXIDATION | VANDERBILT UNIVERSITY | 2008-09-18 | — | — | US | disclosed |
| US-20080227776-A1 | INHIBITORS OF HEMEPROTEIN-CATALYZED LIPID PEROXIDATION | VANDERBILT UNIVERSITY | 2008-09-18 | — | — | US | disclosed |
| EP-1740685-A1 | ANTIOXIDANT COMPOSITIONS | The Procter and Gamble Company (US) | 2007-01-10 | — | — | EP | disclosed |
| WO-2005105966-A1 | ANTIOXIDANT COMPOSITIONS | THE PROCTER & GAMBLE COMPANY (US) | 2005-11-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10675285-B2 | Inhibitors of hemeprotein-catalyzed lipid peroxidation | HMOX1, GPX4, HMOX2 | MEN1 4839/4885KMT2A 4646/4885CA1 2750/4885 |
| US-20080227776-A1 | INHIBITORS OF HEMEPROTEIN-CATALYZED LIPID PEROXIDATION | HMOX1, GPX4, HMOX2 | MEN1 4839/4885KMT2A 4646/4885CA1 2750/4885 |
| US-20160067256-A1 | Inhibitors of Hemeprotein-Catalyzed Lipid Peroxidation | HMOX1, GPX4, HMOX2 | MEN1 4839/4885KMT2A 4646/4885CA1 2750/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.