Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 14/20 | 0.67 |
| ▸ | CA2 | P00918 | 14/20 | 0.67 |
| ▸ | CA9 | Q16790 | 8/20 | 0.67 |
| ▸ | CA5A | P35218 | 5/20 | 0.67 |
| ▸ | CA7 | P43166 | 4/20 | 0.67 |
| ▸ | CA4 | P22748 | 4/20 | 0.67 |
| ▸ | CA6 | P23280 | 4/20 | 0.67 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.67 |
| ▸ | CA12 | O43570 | 3/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | PLA2G7 | Q13093 | 1/20 | 0.47 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | NT5E | P21589 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | MTOR | P42345 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HTR6 | P50406 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Benzene SCHEMBL6258462 | 1.00 | CA1 (0.67) | CA1CA2CA9CA5ACA7 | |
| Benzene SCHEMBL10457003 | 1.00 | CA1 (0.67) | CA1CA2CA9CA5ACA7 | |
| Sulfamide SCHEMBL5880 | 0.82 | — | — | |
| Benzene SCHEMBL2344334 | 0.80 | CA1 (0.73) | CA1CA2CA9CA5ACA7 | |
| Benzene SCHEMBL17784484 | 0.80 | CA1 (0.42) | CA1CA2CA9CA5ACA7 | |
| Benzene SCHEMBL6661878 | 0.80 | CA1 (0.73) | CA1CA2CA9CA5ACA7 | |
| Biphenyl SCHEMBL187355 | 0.78 | CA2 (0.67) | CA1CA2CA9CA5ACA7 | |
| Pyridine SCHEMBL11570751 | 0.78 | NAPRT (0.60) | CA1CA2CA9CA5ACA7 | |
| Benzene SCHEMBL28967058 | 0.77 | CA2 (0.40) | CA1CA2CA9CA5ACA7 | |
| Sulfamide SCHEMBL3409127 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 91 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103893178-B | Benzene-sulfamide compound is in the application prepared in anti-HIV-1 virus drugs | Guangzhou Zhongheng Electronic Technology Co.,Ltd. (CN) | 2016-06-01 | — | — | CN | claimed |
| CN-103893178-A | Application of benzene-sulfamide compounds in preparing anti-HIV-1(human immunodeficiency virus-1) drug | UNIV SUN YAT SEN | 2014-07-02 | — | — | CN | claimed |
| EP-0275918-B1 | PROCESS FOR THE PREPARATION OF IMIDIZED ACRYLIC POLYMERS | ATOCHEM INDUSTRIALE s.r.l. (IT) | 1992-03-25 | — | — | EP | claimed |
| US-4968755-A | Imidized acrylic polymers and process for their preparation | VEDRIL S.P.A. (IT) | 1990-11-06 | — | — | US | claimed |
| EP-0275918-A2 | Process for the preparation of imidized acrylic polymers | ATOCHEM INDUSTRIALE s.r.l. (IT) | 1988-07-27 | — | — | EP | claimed |
| EP-0073463-B1 | INSERTION COMPOUNDS, INTERCALATION COMPOUNDS AND SOLID SOLUTIONS OF COLOURED METALLIC ORGANIC DERIVATIVES | BAYER AG (DE) | 1985-10-23 | — | — | EP | claimed |
| JP-8295078-A | — | — | None | — | — | JP | disclosed |
| EP-4389711-A1 | PROCESS OF DECONTAMINATION OF A RECOVERED CELLULOSIC WASTE STREAM FOR ITS SUBSEQUENT TRANSFORMATION INTO FERMENTABLE SUGARS | INSTITUTO TECNOLÓGICO DEL EMBALAJE, TRANSPORTE Y LOGÍSTICA (ITENE) (ES) | 2024-06-26 | — | — | EP | disclosed |
| CN-113897603-A | Corrosion-resistant palladium electroless plating solution and application thereof | 信丰正天伟电子科技有限公司 | 2022-01-07 | — | — | CN | disclosed |
| CN-110128396-B | Xanthone bridged sulfonamide derivative and preparation method and application thereof | 中山大学 | 2021-05-18 | — | — | CN | disclosed |
| US-10080742-B2 | Isoxazole derivatives as FXR agonists and methods of use thereof | ENANTA PHARMACEUTICALS, INC. (US) | 2018-09-25 | — | — | US | disclosed |
| CN-108276376-A | Novel two allyl benzene derivatives of one kind and preparation method thereof, a kind of pharmaceutical composition | 北京理工大学 | 2018-07-13 | — | — | CN | disclosed |
| US-9927697-B2 | Mask blank, method of manufacturing mask blank and method of manufacturing transfer mask | HOYA CORPORATION (JP) | 2018-03-27 | — | — | US | disclosed |
| EP-0275918-A2 | Process for the preparation of imidized acrylic polymers | ATOCHEM INDUSTRIALE s.r.l. (IT) | 1988-07-27 | — | — | EP | disclosed |
| US-4729936-A | WIDE TEMPERATURE RANGE, PYRAZOLE COMPOUNDS | FUJI PHOTO FILM CO., LTD. (JP) | 1988-03-08 | — | — | US | disclosed |
| EP-0244177-A2 | Method for processing light-sensitive silver halide color photographic material | KONICA CORPORATION (JP) | 1987-11-04 | — | — | EP | disclosed |
| US-4695525-A | HEAT DEVELOPMENT, PYRAZOLONE | FUJI PHOTO FILM CO., LTD. (JP) | 1987-09-22 | — | — | US | disclosed |
| US-4642247-A | PROPELLING INK DROPLETS ON SUBSTRATE HAVING WATER-SORPTIVE UNDERLAYER, WATER RESISTANT COVER LAYER | CANON KABUSHIKI KAISHA (JP) | 1987-02-10 | — | — | US | disclosed |
| EP-0205079-A2 | Acid disulfimide triphenodioxazine dyes | BAYER AG (DE) | 1986-12-17 | — | — | EP | disclosed |
| US-4001290-A | LACQUERS, COATINGS, ADHESIVES, TELOMERS, FOAM PLASTICS | BAYER AKTIENGESELLSCHAFT (DT) | 1977-01-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10080742-B2 | Isoxazole derivatives as FXR agonists and methods of use thereof | FXR1, SLC10A1, NR1H4 | CA1 2185/4885CA2 2111/4885CA9 2927/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.