Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIT | P10721 | 7/20 | 0.36 |
| ▸ | GRM5 | P41594 | 11/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20676492 | 1.00 | KIT (0.36) | KITGRM5KCNH2 | |
| SCHEMBL20116496 | 0.82 | GRM5 (0.37) | GRM5KCNH2 | |
| SCHEMBL20116829 | 0.82 | GRM5 (0.37) | GRM5KCNH2 | |
| SCHEMBL20116617 | 0.82 | GRM5 (0.37) | GRM5KCNH2 | |
| SCHEMBL20116821 | 0.76 | KIT (0.39) | KIT | |
| SCHEMBL20116807 | 0.76 | KIT (0.39) | KIT | |
| SCHEMBL20676518 | 0.76 | KIT (0.38) | KIT | |
| SCHEMBL20117282 | 0.73 | LDHA (0.41) | KIT | |
| SCHEMBL22358225 | 0.73 | GRM5 (0.40) | GRM5KCNH2 | |
| SCHEMBL20116710 | 0.72 | GRM5 (0.39) | GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | JANSSEN PHARMACEUTICA NV (BE) | 2024-01-16 | — | — | US | disclosed |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | JANSSEN PHARMACEUTICA NV (BE) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11873298-B2 | Compounds and uses thereof | NLN, ACHE, CLN6 | KIT 4491/4885GRM5 68/4885KCNH2 1329/4885 |
| US-20200262828-A1 | COMPOUNDS AND USES THEREOF | NLN, ACHE, CLN6 | KIT 4491/4885GRM5 68/4885KCNH2 1329/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.