Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 11/20 | 0.45 |
| ▸ | IL6 | P05231 | 4/20 | 0.45 |
| ▸ | MAOB | P27338 | 4/20 | 0.44 |
| ▸ | MAOA | P21397 | 3/20 | 0.44 |
| ▸ | ACHE | P22303 | 5/20 | 0.43 |
| ▸ | BCHE | P06276 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29034560 | 0.89 | CHRM4 (0.48) | TLR7IL6ACHECHRM4 | |
| SCHEMBL26347258 | 0.87 | TLR7 (0.61) | TLR7IL6TLR8 | |
| SCHEMBL29475661 | 0.87 | ACHE (0.47) | TLR7IL6MAOBMAOAACHE | |
| SCHEMBL29034548 | 0.87 | CHRM4 (0.47) | TLR7IL6ACHECHRM4 | |
| SCHEMBL29034555 | 0.87 | ACHE (0.47) | TLR7IL6MAOBMAOAACHE | |
| SCHEMBL22359264 | 0.85 | ACHE (0.46) | TLR7IL6ACHECHRM4 | |
| SCHEMBL29034532 | 0.83 | CHRM4 (0.44) | TLR7IL6ACHECHRM4 | |
| SCHEMBL29034540 | 0.83 | TLR7 (0.43) | TLR7IL6ACHEBCHETLR8 | |
| SCHEMBL29034541 | 0.83 | TLR7 (0.43) | TLR7IL6ACHEBCHETLR8 | |
| SCHEMBL29475671 | 0.83 | TLR7 (0.43) | TLR7IL6ACHEBCHETLR8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020168017-A1 | COMPOSITIONS CONTAINING, METHODS AND USES OF ANTIBODY-TLR AGONIST CONJUGATES | AMBRX, INC. (US) | 2020-08-20 | — | — | WO | disclosed |