Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 12/20 | 1.00 |
| ▸ | TMIGD3 | P0DMS9 | 10/20 | 1.00 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.83 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16774254 | 1.00 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1 | |
| SCHEMBL16774149 | 0.93 | ADORA3 (1.00) | ADORA3TMIGD3ADORA1 | |
| SCHEMBL16774191 | 0.91 | ADORA3 (1.00) | ADORA3TMIGD3 | |
| SCHEMBL24615097 | 0.87 | TMIGD3 (1.00) | ADORA3TMIGD3 | |
| SCHEMBL21779335 | 0.87 | TMIGD3 (1.00) | ADORA3TMIGD3 | |
| SCHEMBL16774186 | 0.87 | TMIGD3 (1.00) | ADORA3TMIGD3 | |
| SCHEMBL22359917 | 0.87 | ADORA3 (0.77) | ADORA3TMIGD3ADORA1 | |
| SCHEMBL16774325 | 0.87 | ADORA3 (0.77) | ADORA3TMIGD3ADORA1 | |
| SCHEMBL20122115 | 0.86 | TMIGD3 (1.00) | ADORA3TMIGD3 | |
| SCHEMBL16774176 | 0.86 | TMIGD3 (1.00) | ADORA3TMIGD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220117985-A1 | TREATMENT OF CHRONIC HEADACHES | UNIVERSITY OF MARYLAND, BALTIMORE | 2022-04-21 | — | — | US | disclosed |
| WO-2020168274-A1 | TREATMENT OF CHRONIC HEADACHES | SAINT LOUIS UNIVERSITY (US) | 2020-08-20 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220117985-A1 | TREATMENT OF CHRONIC HEADACHES | ADORA3, ADORA2B, ADORA2A | ADORA3 1/4885TMIGD3 1321/4885ADORA1 10/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.