SCHEMBL22360310

SCHEMBL22360310

CO[C@@H]1OC(CO)[C@@H](O[C@@H]2OC(CO)[C@H](O)C(O[C@H]3OC(CO)[C@H](O)C(O)[C@@H]3O)C2O)C(O)C1O

nearest known ligand 0.59

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
▸ LGALS8 O00214 3/20 0.54
▸ LGALS3 P17931 2/20 0.54
▸ LGALS4 P56470 1/20 0.54
▸ ENGASE Q8NFI3 1/20 0.51
▸ LGALS9 O00182 1/20 0.49
▸ LGALS1 P09382 1/20 0.49
▸ LGALS7; LGALS7B P47929 1/20 0.49
▸ MEN1 O00255 1/20 0.49
▸ KMT2A Q03164 1/20 0.49
▸ CD209 Q9NNX6 1/20 0.48
▸ AMY2A P04746 1/20 0.48
▸ AMY1A P0DUB6 1/20 0.48
▸ FGF1 P05230 1/20 0.46
▸ FGF2 P09038 1/20 0.46
▸ VEGFA P15692 1/20 0.46
▸ HPSE Q9Y251 1/20 0.46
▸ TYR P14679 4/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18680391 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4ENGASELGALS9
SCHEMBL13030148 1.00 LGALS8 (0.54) LGALS8LGALS3LGALS4ENGASELGALS9
SCHEMBL6820046 0.95 LGALS8 (0.56) LGALS8LGALS3LGALS4ENGASELGALS9
SCHEMBL4285005 0.95 LGALS8 (0.56) LGALS8LGALS3LGALS4ENGASELGALS9
SCHEMBL13125623 0.95 LGALS8 (0.58) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL23475838 0.95 LGALS8 (0.58) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL15730308 0.95 LGALS8 (0.56) LGALS8LGALS3LGALS4ENGASELGALS9
SCHEMBL12070983 0.95 LGALS8 (0.58) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL20658640 0.95 LGALS8 (0.58) LGALS8LGALS3LGALS4LGALS9LGALS1
SCHEMBL7871307 0.95 LGALS8 (0.58) LGALS8LGALS3LGALS4LGALS9LGALS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200262881-A1 pHLIP-Mediated Carbohydrate Tethering at Cell Surfaces to Induce Immune Response UNIVERSITY OF RHODE ISLAND BOARD OF TRUSTEES 2020-08-20 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200262881-A1 pHLIP-Mediated Carbohydrate Tethering at Cell Surfaces to Induce Immune Response PHLPP1, CD4, CD14 LGALS8 100/4885LGALS3 133/4885LGALS4 117/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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