Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.45 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | MGAM | O43451 | 1/20 | 0.45 |
| ▸ | SI | P14410 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | SHMT1 | P34896 | 2/20 | 0.33 |
| ▸ | SHMT2 | P34897 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NCOA2 | Q15596 | 1/20 | 0.32 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360429 | 0.91 | AGPAT2 (0.36) | KDM4EALDH1A1GAAMGAMSI | |
| SCHEMBL22360427 | 0.81 | PTGS1 (0.30) | PTGS1HRH3 | |
| SCHEMBL22360425 | 0.80 | MAPT (0.44) | KDM4EALDH1A1GAAMGAMSI | |
| SCHEMBL22360430 | 0.80 | NPC1 (0.39) | ALDH1A1GAAMAPTKMT2ACYP3A4 | |
| SCHEMBL22360415 | 0.76 | ALDH1A1 (0.38) | KDM4EALDH1A1GAARAB9AMAPT | |
| SCHEMBL22360488 | 0.75 | SMN1; SMN2 (0.50) | KDM4EALDH1A1RAB9AMAPTL3MBTL1 | |
| SCHEMBL22360387 | 0.75 | ALDH1A1 (0.40) | ALDH1A1GAAMGAMSIRAB9A | |
| SCHEMBL22360421 | 0.73 | ALDH1A1 (0.40) | KDM4EALDH1A1GAARAB9AMAPT | |
| SCHEMBL22360417 | 0.73 | HDAC1 (0.37) | KDM4EALDH1A1GAAMGAMSI | |
| SCHEMBL22360426 | 0.71 | KDM4E (0.45) | KDM4EALDH1A1RAB9AMAPTTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164403-A1 | 1,1-DICYANO-OXIME-ETHER COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-08-20 | — | — | WO | disclosed |