Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 4/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | SI | P14410 | 1/20 | 0.34 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.34 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.33 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | KMO | O15229 | 2/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.32 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.32 |
| ▸ | HPN | P05981 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22360427 | 0.84 | PTGS1 (0.30) | — | |
| SCHEMBL22360429 | 0.82 | AGPAT2 (0.36) | MAPTKDM4EALDH1A1L3MBTL1MGAM | |
| SCHEMBL22360417 | 0.81 | HDAC1 (0.37) | MAPTKDM4EALDH1A1MGAMGAA | |
| SCHEMBL22360421 | 0.81 | ALDH1A1 (0.40) | MAPTKDM4EALDH1A1L3MBTL1GAA | |
| SCHEMBL22360387 | 0.81 | ALDH1A1 (0.40) | ALDH1A1L3MBTL1MGAMGAASI | |
| SCHEMBL22360430 | 0.81 | NPC1 (0.39) | MAPTALDH1A1GAA | |
| SCHEMBL22360424 | 0.80 | KDM4E (0.45) | MAPTKDM4EALDH1A1L3MBTL1MGAM | |
| SCHEMBL22360428 | 0.80 | ALDH1A1 (0.45) | MAPTKDM4EALDH1A1GAALMNA | |
| SCHEMBL22360426 | 0.80 | KDM4E (0.45) | MAPTKDM4EALDH1A1LMNAHPGD | |
| SCHEMBL22360423 | 0.79 | HDAC1 (0.40) | MAPTKDM4EALDH1A1GAAS1PR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2020164403-A1 | 1,1-DICYANO-OXIME-ETHER COMPOUND AND APPLICATION THEREOF | 沈阳化工大学 | 2020-08-20 | — | — | WO | disclosed |