Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | MAPT | P10636 | 1/20 | 0.54 |
| ▸ | RAB9A | P51151 | 1/20 | 0.54 |
| ▸ | HTT | P42858 | 2/20 | 0.47 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.46 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.44 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28167261 | 0.78 | HTT (0.62) | POLBMAPTRAB9AHTTROCK1 | |
| SCHEMBL20603971 | 0.76 | POLB (0.60) | POLBMAPTRAB9AHTTROCK1 | |
| SCHEMBL30419394 | 0.76 | POLB (0.60) | POLBMAPTRAB9AHTTROCK1 | |
| SCHEMBL10549917 | 0.76 | FGFR1 (0.57) | POLBMAPTRAB9AHTTROCK1 | |
| SCHEMBL17265639 | 0.75 | POLB (0.58) | POLBMAPTRAB9AHTTROCK1 | |
| SCHEMBL22360756 | 0.75 | RAB9A (0.56) | POLBMAPTRAB9AHTT | |
| SCHEMBL31241183 | 0.75 | POLB (0.67) | POLBMAPTRAB9AHTTROCK1 | |
| SCHEMBL19459554 | 0.74 | ALDH1A1 (0.60) | POLBMAPTRAB9AHTTFGFR1 | |
| SCHEMBL17077632 | 0.74 | MAPT (0.74) | POLBMAPTRAB9AHTTORAI1 | |
| SCHEMBL10552778 | 0.73 | POLB (0.55) | POLBMAPTRAB9AHTTROCK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11724982-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-08-15 | — | — | US | disclosed |
| US-20200262784-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262784-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | AHR, AFF2, AFF4 | POLB 3040/4885MAPT 3670/4885RAB9A 1219/4885 |
| US-11724982-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | AHR, AFF2, AFF4 | POLB 3040/4885MAPT 3670/4885RAB9A 1219/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.