Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.42 |
| ▸ | MAPK8 | P45983 | 7/20 | 0.38 |
| ▸ | MAPK9 | P45984 | 7/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 6/20 | 0.38 |
| ▸ | CDK2 | P24941 | 6/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.38 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12175465 | 0.77 | RAB9A (0.61) | RAB9ASMN1; SMN2TSHRKCNMA1MAPK8 | |
| SCHEMBL20156597 | 0.77 | RAB9A (0.61) | RAB9ASMN1; SMN2TSHRKCNMA1MAPK8 | |
| SCHEMBL11612094 | 0.77 | RAB9A (0.61) | RAB9ASMN1; SMN2TSHRKCNMA1MAPK8 | |
| SCHEMBL22360751 | 0.75 | POLB (0.55) | RAB9AMAPTPOLBHTT | |
| SCHEMBL17681658 | 0.74 | ALDH1A1 (0.58) | RAB9AALDH1A1KMT2AMEN1CYP2C9 | |
| SCHEMBL678640 | 0.73 | RAB9A (1.00) | RAB9ASMN1; SMN2TSHRKCNMA1MAPK8 | |
| SCHEMBL30355239 | 0.73 | RAB9A (1.00) | RAB9ASMN1; SMN2TSHRKCNMA1MAPK8 | |
| SCHEMBL18517578 | 0.71 | RAB9A (0.54) | RAB9ASMN1; SMN2TSHRKCNMA1MAPK8 | |
| SCHEMBL22605443 | 0.71 | RAB9A (0.64) | RAB9ASMN1; SMN2TSHRMAPK8MAPK9 | |
| SCHEMBL17681659 | 0.71 | RAB9A (0.54) | RAB9ASMN1; SMN2TSHRKCNMA1MAPK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11724982-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2023-08-15 | — | — | US | disclosed |
| US-20200262784-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | THE RESEARCH FOUNDATION FOR THE STATE UNIVERSITY OF NEW YORK (US) | 2020-08-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200262784-A1 | TRIFLUOROMETHOXYLATION OF ARENES VIA INTRAMOLECULAR TRIFLUOROMETHOXY GROUP MIGRATION | AHR, AFF2, AFF4 | RAB9A 1219/4885SMN1; SMN2 2278/4885TSHR 490/4885 |
| US-11724982-B2 | Trifluoromethoxylation of arenes via intramolecular trifluoromethoxy group migration | AHR, AFF2, AFF4 | RAB9A 1219/4885SMN1; SMN2 2278/4885TSHR 490/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.