Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.73 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | LMNA | P02545 | 2/20 | 0.73 |
| ▸ | HTT | P42858 | 2/20 | 0.73 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.73 |
| ▸ | APAF1 | O14727 | 1/20 | 0.73 |
| ▸ | MITF | O75030 | 1/20 | 0.73 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.73 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.73 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | CDC25B | P30305 | 6/20 | 0.56 |
| ▸ | S100A4 | P26447 | 4/20 | 0.56 |
| ▸ | IDO1 | P14902 | 1/20 | 0.55 |
| ▸ | TDO2 | P48775 | 1/20 | 0.55 |
| ▸ | CDC25A | P30304 | 4/20 | 0.53 |
| ▸ | MAP2K7 | O14733 | 2/20 | 0.53 |
| ▸ | PKM | P14618 | 4/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10956396 | 0.93 | KDM4E (0.63) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL13675411 | 0.84 | LMNA (0.57) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL10909742 | 0.82 | ALDH1A1 (0.52) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL13649357 | 0.82 | MAPT (0.59) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL16473013 | 0.80 | STAT3 (0.54) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL30005823 | 0.80 | MAPT (0.56) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL12354328 | 0.80 | ALDH1A1 (0.60) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL4446630 | 0.80 | MAPT (0.56) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL10446741 | 0.79 | MAPT (0.59) | MAPTKDM4EALDH1A1LMNAHTT | |
| SCHEMBL11421782 | 0.78 | MAPT (0.55) | MAPTKDM4EALDH1A1LMNAHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011098545-A1 | NOVEL 2-METHYL-1,4-NAPHTHOQUINONE DERIVATIVES AND PRECURSORS THEREOF, HAVING VITAMIN K ACTIVITY | NATTOPHARMA ASA (NO) | 2011-08-18 | — | — | WO | claimed |
| WO-2011098545-A1 | NOVEL 2-METHYL-1,4-NAPHTHOQUINONE DERIVATIVES AND PRECURSORS THEREOF, HAVING VITAMIN K ACTIVITY | NATTOPHARMA ASA (NO) | 2011-08-18 | — | — | WO | disclosed |
| WO-2011098545-A1 | NOVEL 2-METHYL-1,4-NAPHTHOQUINONE DERIVATIVES AND PRECURSORS THEREOF, HAVING VITAMIN K ACTIVITY | NATTOPHARMA ASA (NO) | 2011-08-18 | — | — | WO | disclosed |