Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 15/20 | 0.60 |
| ▸ | SLC2A1 | P11166 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365329 | 0.91 | FFAR1 (0.66) | FFAR1 | |
| SCHEMBL22365291 | 0.88 | FFAR1 (0.58) | FFAR1 | |
| SCHEMBL22365350 | 0.86 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL22365303 | 0.84 | FFAR1 (0.62) | FFAR1 | |
| SCHEMBL22365412 | 0.82 | FFAR1 (0.61) | FFAR1 | |
| SCHEMBL22365447 | 0.82 | GPR88 (0.43) | FFAR1 | |
| SCHEMBL22365454 | 0.82 | FFAR1 (0.42) | FFAR1 | |
| SCHEMBL22365407 | 0.81 | FFAR1 (0.43) | FFAR1 | |
| SCHEMBL22365237 | 0.80 | ACACA (0.50) | SLC2A1KDM5AKDM4C | |
| SCHEMBL17000290 | 0.80 | FFAR1 (0.85) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102198-B1 | ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-08-26 | — | — | EP | disclosed |