Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 10/20 | 0.42 |
| ▸ | ACACA | Q13085 | 4/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22365447 | 0.91 | GPR88 (0.43) | FFAR1ACACAACACBALDH1A1TAAR1 | |
| SCHEMBL22365407 | 0.90 | FFAR1 (0.43) | FFAR1ACACAACACBTAAR1 | |
| SCHEMBL22365237 | 0.89 | ACACA (0.50) | ACACAACACB | |
| SCHEMBL22365350 | 0.87 | FFAR1 (0.56) | FFAR1 | |
| SCHEMBL22365452 | 0.86 | ALDH1A1 (0.41) | FFAR1ACACAACACBALDH1A1TAAR1 | |
| SCHEMBL22365453 | 0.85 | FFAR1 (0.60) | FFAR1ACACB | |
| SCHEMBL22365291 | 0.85 | FFAR1 (0.58) | FFAR1ALDH1A1TAAR1 | |
| SCHEMBL22365225 | 0.85 | FFAR1 (0.58) | FFAR1 | |
| SCHEMBL22365317 | 0.82 | SLC6A2 (0.48) | ACACAACACB | |
| SCHEMBL22365266 | 0.81 | FFAR1 (0.58) | FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3102198-B1 | ANTIDIABETIC COMPOUNDS | MERCK SHARP & DOHME (US) | 2020-08-26 | — | — | EP | disclosed |