Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC1A5 | Q15758 | 8/20 | 0.45 |
| ▸ | ARG1 | P05089 | 1/20 | 0.43 |
| ▸ | NOS3 | P29474 | 1/20 | 0.41 |
| ▸ | NOS1 | P29475 | 1/20 | 0.41 |
| ▸ | NOS2 | P35228 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 3/20 | 0.39 |
| ▸ | BHMT | Q93088 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15209210 | 1.00 | SLC1A5 (0.45) | SLC1A5ARG1NOS3NOS1NOS2 | |
| SCHEMBL2237999 | 0.90 | NOS2 (0.50) | SLC1A5ARG1NOS3NOS1NOS2 | |
| SCHEMBL2236959 | 0.89 | ARG1 (0.47) | SLC1A5ARG1NOS3NOS1NOS2 | |
| SCHEMBL2236655 | 0.83 | PPARG (0.50) | SLC1A5KIF11 | |
| SCHEMBL15208842 | 0.83 | CYP1A2 (0.39) | SLC1A5ARG1KIF11CYP1A2 | |
| SCHEMBL31369757 | 0.78 | KIF11 (0.47) | SLC1A5NOS3NOS1NOS2KIF11 | |
| SCHEMBL2238701 | 0.75 | SLC1A5 (0.56) | SLC1A5 | |
| SCHEMBL15208822 | 0.75 | SLC1A5 (0.56) | SLC1A5 | |
| SCHEMBL13585354 | 0.74 | ARG1 (0.39) | SLC1A5ARG1NOS3NOS1NOS2 | |
| SCHEMBL2236628 | 0.74 | PPARG (0.53) | SLC1A5ARG1NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2531520-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | Polyphor AG (CH) | 2012-12-12 | — | — | EP | disclosed |
| WO-2011095607-A1 | TEMPLATE-FIXED PEPTIDOMIMETICS WITH CXCR7 MODULATING ACTIVITY | POLYPHOR AG (CH) | 2011-08-11 | — | — | WO | disclosed |