Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 11/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | EGFR | P00533 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23366502 | 0.99 | ABCG2 (0.39) | ABCG2KDM4EHTTEGFR | |
| Iodide SCHEMBL22366566 | 0.89 | ADRB2 (0.33) | — | |
| SCHEMBL23366511 | 0.88 | ADRB2 (0.33) | — | |
| SCHEMBL16525722 | 0.85 | — | — | |
| Iodide SCHEMBL16516486 | 0.82 | ADRB2 (0.32) | — | |
| Iodide SCHEMBL30731322 | 0.77 | LTA4H (0.39) | — | |
| Bicarbonate SCHEMBL29765552 | 0.75 | ADRB2 (0.32) | KDM4E | |
| Bicarbonate SCHEMBL26607968 | 0.75 | ADRB2 (0.32) | KDM4E | |
| Iodide SCHEMBL21046358 | 0.73 | CASR (0.35) | — | |
| SCHEMBL21046373 | 0.71 | HTT (0.36) | KDM4EHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12055517-B2 | Graphene transistor comprising functionalized N-heterocyclic carbene compound, fabrication method therefor, and biosensor comprising same | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2024-08-06 | — | — | US | disclosed |
| EP-3703134-B1 | BIOSENSOR COMPRISING GRAPHENE TRANSISTOR FUNCTIONALIZED WITH N-HETEROCYCLIC CARBENE COMPOUND AND FABRICATION METHOD THEREFOR | KOREA RES INST BIOSCIENCE & BIOTECHNOLOGY (KR) | 2024-04-17 | — | — | EP | disclosed |
| US-20210181147-A1 | GRAPHENE TRANSISTOR COMPRISING FUNCTIONALIZED N-HETEROCYCLIC CARBENE COMPOUND, FABRICATION METHOD THEREFOR, AND BIOSENSOR COMPRISING SAME | KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY (KR) | 2021-06-17 | — | — | US | disclosed |
| EP-3703134-A1 | GRAPHENE TRANSISTOR COMPRISING FUNCTIONALIZED N-HETEROCYCLIC CARBENE COMPOUND, FABRICATION METHOD THEREFOR, AND BIOSENSOR COMPRISING SAME | Korea Research Institute of Bioscience and Biotechnology (KR) | 2020-09-02 | — | — | EP | disclosed |