Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASR | P41180 | 1/20 | 0.35 |
| ▸ | LSS | P48449 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.31 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.31 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.30 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18844474 | 0.99 | CASR (0.36) | CASRLSSALDH1A1L3MBTL1ALDH2 | |
| Iodide SCHEMBL30731322 | 0.86 | LTA4H (0.39) | CASRL3MBTL1 | |
| SCHEMBL17916653 | 0.85 | LTA4H (0.40) | CASRL3MBTL1 | |
| SCHEMBL21046373 | 0.80 | HTT (0.36) | MAOB | |
| Iodide SCHEMBL22366566 | 0.79 | ADRB2 (0.33) | — | |
| Bicarbonate SCHEMBL21046372 | 0.78 | FGFR1 (0.35) | MAOB | |
| Iodide SCHEMBL22366569 | 0.76 | L3MBTL1 (0.45) | L3MBTL1MAOB | |
| Trifluoromethanesulfonic Acid SCHEMBL21046347 | 0.75 | MOGAT2 (0.39) | — | |
| Iodide SCHEMBL22366562 | 0.73 | ABCG2 (0.39) | — | |
| Bicarbonate SCHEMBL29765454 | 0.70 | TP53 (0.41) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2021-05-18 | — | — | US | disclosed |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | QUEEN'S UNIVERSITY AT KINGSTON (CA) | 2019-06-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11008291-B2 | Methods of forming carbene-functionalized composite materials | VCL, CHN2, CA3 | CASR 1905/4885LSS 1340/4885ALDH1A1 2011/4885 |
| US-20190169132-A1 | Methods of Forming Carbene-Functionalized Composite Materials | VCL, CHN2, CA3 | CASR 1905/4885LSS 1340/4885ALDH1A1 2011/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.