Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.44 |
| ▸ | SCN9A | Q15858 | 11/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.42 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.42 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.42 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24987866 | 0.91 | MRGPRX4 (0.46) | MAPTMRGPRX4GAA | |
| SCHEMBL30185255 | 0.91 | MRGPRX4 (0.46) | MAPTMRGPRX4GAA | |
| SCHEMBL30185239 | 0.90 | LRRK2 (0.45) | LRRK2CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL24986659 | 0.90 | LRRK2 (0.45) | LRRK2CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL24986742 | 0.89 | MRGPRX4 (0.42) | LRRK2MAPTMRGPRX4HDAC3HDAC1 | |
| SCHEMBL24987876 | 0.88 | MRGPRX4 (0.46) | LRRK2CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL30185149 | 0.88 | MRGPRX4 (0.46) | LRRK2CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL24985500 | 0.83 | MAPT (0.47) | LRRK2CYP1A2CYP3A4CYP2C19MAPT | |
| SCHEMBL24985107 | 0.82 | CRHR1 (0.44) | CYP1A2CYP3A4CYP2C19MAPTCYP2C9 | |
| SCHEMBL30185197 | 0.82 | CRHR1 (0.44) | CYP1A2CYP3A4CYP2C19MAPTCYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
| EP-3700340-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | Dow Agrosciences LLC (US) | 2020-09-02 | — | — | EP | disclosed |
| CN-111278283-A | Pyridine and pyrimidine formate herbicides and methods of use thereof | 美国陶氏益农公司 | 2020-06-12 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | LRRK2 4604/4885CYP1A2 298/4885CYP3A4 239/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.