Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MRGPRX4 | Q96LA9 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24987876 | 1.00 | MRGPRX4 (0.46) | MRGPRX4MAPTCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL30185255 | 0.90 | MRGPRX4 (0.46) | MRGPRX4MAPTNPSR1MAPK1GAA | |
| SCHEMBL24987866 | 0.90 | MRGPRX4 (0.46) | MRGPRX4MAPTNPSR1MAPK1GAA | |
| SCHEMBL22366823 | 0.88 | LRRK2 (0.47) | MRGPRX4MAPTCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL24984357 | 0.82 | MRGPRX4 (0.45) | MRGPRX4MAPTCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL24986742 | 0.81 | MRGPRX4 (0.42) | MRGPRX4MAPTLRRK2HDAC3HDAC1 | |
| SCHEMBL30185239 | 0.80 | LRRK2 (0.45) | MRGPRX4MAPTCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL24986659 | 0.80 | LRRK2 (0.45) | MRGPRX4MAPTCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL24985506 | 0.79 | MRGPRX4 (0.43) | MRGPRX4MAPTCYP2C9CYP2C19CYP1A2 | |
| SCHEMBL24987896 | 0.78 | NPSR1 (0.45) | MRGPRX4MAPTCYP2C9CYP2C19CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | DOW AGROSCIENCES LLC (US) | 2023-01-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230017045-A1 | PYRIDINE AND PYRIMIDINE CARBOXYLATE HERBICIDES AND METHODS OF USE THEREOF | PDXK, DPYD, DDT | MRGPRX4 1870/4885MAPT 3017/4885CYP2C9 171/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.