Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PYCR1 | P32322 | 1/20 | 0.47 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | BCAT2 | O15382 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.37 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.37 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.37 |
| ▸ | NAAA | Q02083 | 1/20 | 0.37 |
| ▸ | EDNRB | P24530 | 2/20 | 0.37 |
| ▸ | EDNRA | P25101 | 2/20 | 0.37 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Formaldehyde SCHEMBL27932210 | 0.94 | PDPK1 (0.44) | PYCR1PDPK1KDM1ABCAT2AKR1B1 | |
| SCHEMBL6691430 | 0.88 | TYR (0.47) | PYCR1PDPK1KDM1ANPC1RAB9A | |
| SCHEMBL223670 | 0.86 | TYR (0.47) | PYCR1PDPK1KDM1ABCAT2MTNR1B | |
| SCHEMBL13464690 | 0.85 | TYR (0.50) | PYCR1PDPK1MTNR1B | |
| SCHEMBL13464625 | 0.85 | TYR (0.50) | PYCR1PDPK1MTNR1B | |
| SCHEMBL9710376 | 0.85 | TYR (0.50) | PYCR1PDPK1MTNR1B | |
| SCHEMBL30294101 | 0.85 | TYR (0.50) | PYCR1PDPK1MTNR1B | |
| SCHEMBL31555026 | 0.83 | DPP4 (0.38) | PYCR1DGAT1EDNRBEDNRA | |
| SCHEMBL1310479 | 0.83 | PYCR1 (0.50) | PYCR1PDPK1KDM1AAKR1B1P2RX7 | |
| SCHEMBL2298211 | 0.81 | PDPK1 (0.45) | PYCR1PDPK1KDM1ANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117720932-A | Negative liquid crystal compound, liquid crystal composition and application thereof | 安徽宇贝新材料科技有限公司 | 2024-03-19 | — | — | CN | disclosed |
| CN-116710446-A | Crystal forms of GLP-1R agonist and application thereof | 上海齐鲁锐格医药研发有限公司 | 2023-09-05 | — | — | CN | disclosed |
| EP-2669263-B1 | COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2017-11-22 | — | — | EP | disclosed |
| EP-2669263-B1 | COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2017-11-22 | — | — | EP | disclosed |
| US-20170050950-A1 | AROMATIC HETEROCYCLIC COMPOUND | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-02-23 | — | — | US | disclosed |
| US-9546155-B2 | Aromatic heterocyclic compound | MITSUBISHI TANABE PHARMA CORPORATION (JP) | 2017-01-17 | — | — | US | disclosed |
| WO-2015188194-A1 | COMPOSITIONS AND METHODS FOR ENHANCED INTESTINAL ABSORPTION OF CONJUGATED OLIGOMERIC COMPOUNDS | ISIS PHARMACEUTICALS, INC. (US) | 2015-12-10 | — | — | WO | disclosed |
| WO-2015179693-A1 | CONJUGATED ANTISENSE COMPOUNDS AND THEIR USE | ISIS PHARMACEUTICALS, INC. (US) | 2015-11-26 | — | — | WO | disclosed |
| US-9193908-B2 | Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2015-11-24 | — | — | US | disclosed |
| US-9193908-B2 | Compound having dihydrophenanthrene, liquid crystal composition and liquid crystal display device | JNC CORPORATION (JP) | 2015-11-24 | — | — | US | disclosed |
| WO-2012086437-A1 | COMPOUND CONTAINING DIHYDROPHENANTHRENE, LIQUID CRYSTAL COMPOSITION AND LIQUID CRYSTAL DISPLAY | JNC株式会社 (JP) | 2012-06-28 | — | — | WO | disclosed |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | SYNGENTA CROP PROTECTION, INC. (US) | 2010-12-30 | — | — | US | disclosed |
| US-20090325964-A1 | Piperazine Metabotropic Glutamate Receptor 5 (MGLUR5) Negative Allosteric Modulators For Anxiety/Depression | WYETH (US) | 2009-12-31 | — | — | US | disclosed |
| US-7514127-B2 | Dibenzofuran derivatives, dibenzothiophene derivatives and fluorene derivatives | MERCK PATENT GMBH (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7514127-B2 | Dibenzofuran derivatives, dibenzothiophene derivatives and fluorene derivatives | MERCK PATENT GMBH (DE) | 2009-04-07 | — | — | US | disclosed |
| US-7326447-B2 | Benzochromene derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2008-02-05 | — | — | US | disclosed |
| US-7297378-B2 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2007-11-20 | — | — | US | disclosed |
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | MERCK PATENT GMBH (DE) | 2007-09-20 | — | — | US | disclosed |
| US-20050258397-A1 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | MERCK PATENT GMBH (DE) | 2005-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090325964-A1 | Piperazine Metabotropic Glutamate Receptor 5 (MGLUR5) Negative Allosteric Modulators For Anxiety/Depression | GRM5, GRIK5, GRM1 | PYCR1 2537/4885PDPK1 646/4885KDM1A 1431/4885 |
| US-20070219380-A1 | Dibenzofuran Derivatives, Dibenzothiophene Derivatives and Fluorene Derivatives | ZYX, F3, YBX1 | PYCR1 2736/4885PDPK1 3905/4885KDM1A 3653/4885 |
| US-20100331348-A1 | TROPANE DERIVATIVES USEFUL AS PESTICIDES | DDT, ACHE, TPM3 | PYCR1 979/4885PDPK1 1519/4885KDM1A 2060/4885 |
| US-20170050950-A1 | AROMATIC HETEROCYCLIC COMPOUND | GPR119, NR0B1, BET1 | PYCR1 1036/4885PDPK1 3290/4885KDM1A 149/4885 |
| US-20050258397-A1 | Fluorinated fused aromatics and their use in liquid-crystal mixtures | AFF1, AFF2, AFF4 | PYCR1 1607/4885PDPK1 3548/4885KDM1A 2503/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.