Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | MAP4K4 | O95819 | 6/20 | 0.37 |
| ▸ | SMPD3 | Q9NY59 | 3/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.33 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.33 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.33 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.33 |
| ▸ | BMP4 | P12644 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.31 |
| ▸ | DRD4 | P21917 | 1/20 | 0.31 |
| ▸ | DRD3 | P35462 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14249149 | 0.72 | GAA (0.35) | KDM4EMAPTHPGDHSD17B10 | |
| SCHEMBL16863348 | 0.69 | MAP4K4 (0.40) | PDE10ACDK2MAP4K4SMPD3AXL | |
| SCHEMBL19173 | 0.69 | — | — | |
| SCHEMBL1369628 | 0.68 | PDE10A (0.42) | PDE10ACDK2MAP4K4SMPD3AXL | |
| SCHEMBL31674379 | 0.67 | PDE10A (0.45) | PDE10ACDK2MAP4K4SMPD3AXL | |
| SCHEMBL31338725 | 0.67 | PDE10A (0.45) | PDE10ACDK2MAP4K4SMPD3AXL | |
| Hydrochloric Acid SCHEMBL6894527 | 0.67 | PDE10A (0.45) | PDE10ACDK2MAP4K4SMPD3AXL | |
| SCHEMBL27329638 | 0.66 | MAP4K4 (0.35) | MAP4K4HSD17B10HTT | |
| SCHEMBL31752145 | 0.65 | ALDH1A1 (0.36) | MAP4K4KDM4EMAPTHSD17B10HTT | |
| SCHEMBL21067238 | 0.65 | MEN1 (0.41) | MAP4K4PIK3CAKDM4EHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700890-A1 | NEW ALCOXYAMINO DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-09-02 | — | — | EP | claimed |
| EP-3700890-A1 | NEW ALCOXYAMINO DERIVATIVES FOR TREATING PAIN AND PAIN RELATED CONDITIONS | ESTEVE PHARMACEUTICALS, S.A. (ES) | 2020-09-02 | — | — | EP | disclosed |