SCHEMBL31752145

SCHEMBL31752145

Cn1ccn2nccc2c1=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.36
SMN1; SMN2 Q16637 2/20 0.36
HTT P42858 1/20 0.36
HSD17B10 Q99714 1/20 0.36
CYP2C9 P11712 2/20 0.35
CYP1A2 P05177 1/20 0.35
POLB P06746 1/20 0.35
CYP2D6 P10635 1/20 0.35
KDM4E B2RXH2 2/20 0.34
BRD4 O60885 6/20 0.33
LMNA P02545 1/20 0.33
MAPT P10636 1/20 0.33
BRD9 Q9H8M2 2/20 0.32
TAF1 P21675 1/20 0.32
BRPF1 P55201 1/20 0.32
CREBBP Q92793 1/20 0.32
CECR2 Q9BXF3 1/20 0.32
ATAD2 Q6PL18 1/20 0.31
DDB1 Q16531 1/20 0.31
CRBN Q96SW2 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9910062 0.76 ALDH1A1 (0.30) ALDH1A1SMN1; SMN2HTTHSD17B10
SCHEMBL27329638 0.76 MAP4K4 (0.35) ALDH1A1SMN1; SMN2HTTHSD17B10CYP1A2
SCHEMBL21895460 0.74 MAP4K4 (0.40) ALDH1A1SMN1; SMN2HTTHSD17B10KDM4E
SCHEMBL27329520 0.73
SCHEMBL5492782 0.70
Hydrochloric Acid SCHEMBL8978003 0.68 INMT (0.32)
SCHEMBL23679319 0.68 BRD9 (0.32) ALDH1A1LMNAMAPTBRD9
SCHEMBL20586759 0.67 KDM4E (0.37) ALDH1A1SMN1; SMN2KDM4EBRD4MAPT
SCHEMBL24080857 0.67 KDM4E (0.34) ALDH1A1SMN1; SMN2KDM4ELMNAMAPT
SCHEMBL16532135 0.67 LPO (0.44) ALDH1A1SMN1; SMN2CYP2C9POLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260108546-A1 GIP RECEPTOR AGONIST COMPOUNDS LILLY CO ELI (US) 2026-04-23 US disclosed
WO-2025264700-A1 GIP RECEPTOR AGONIST COMPOUNDS ELI LILLY AND COMPANY (US) 2025-12-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260108546-A1 GIP RECEPTOR AGONIST COMPOUNDS GIPR, GLP1R, GCGR ALDH1A1 2982/4885SMN1; SMN2 3292/4885HTT 1368/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.