Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 6/20 | 0.50 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23228246 | 0.86 | LMNA (0.47) | ADKABCB1SLC29A1LMNA | |
| SCHEMBL20058765 | 0.83 | LMNA (0.44) | ADKABCB1SLC29A1LMNA | |
| SCHEMBL30536338 | 0.83 | MEN1 (0.49) | ADKSLC29A1LMNA | |
| SCHEMBL20214417 | 0.83 | MEN1 (0.49) | ADKSLC29A1LMNA | |
| SCHEMBL10131159 | 0.83 | MEN1 (0.49) | ADKSLC29A1LMNA | |
| SCHEMBL10160533 | 0.83 | MEN1 (0.49) | ADKSLC29A1LMNA | |
| SCHEMBL24146505 | 0.81 | PRMT5 (0.46) | ADK | |
| SCHEMBL14644475 | 0.81 | MEN1 (0.45) | ADKABCB1SLC29A1LMNA | |
| SCHEMBL31725319 | 0.79 | LMNA (0.46) | ADKSLC29A1LMNA | |
| SCHEMBL14010232 | 0.78 | GAPDH (0.44) | ADKABCB1SLC29A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3700906-A1 | SELECTIVE INHIBITORS OF PROTEIN ARGININE METHYLTRANSFERASE 5 (PRMT5) | Prelude Therapeutics, Incorporated (US) | 2020-09-02 | — | — | EP | disclosed |