Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | USP2 | O75604 | 1/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAPDH | P04406 | 2/20 | 0.43 |
| ▸ | HRAS | P01112 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.40 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.40 |
| ▸ | P2RX2 | Q9UBL9 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.37 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30536338 | 0.92 | MEN1 (0.49) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL10160533 | 0.92 | MEN1 (0.49) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL20214417 | 0.92 | MEN1 (0.49) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL10131159 | 0.92 | MEN1 (0.49) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL20058765 | 0.91 | LMNA (0.44) | GAPDHHRASLMNAADKALDH1A1 | |
| SCHEMBL23228246 | 0.91 | LMNA (0.47) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL16480678 | 0.90 | ADK (0.51) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL25680026 | 0.86 | P2RX3 (0.39) | GAPDHP2RX3P2RX4P2RX2ADK | |
| SCHEMBL14010232 | 0.86 | GAPDH (0.44) | MEN1USP2POLBKMT2AGAPDH | |
| SCHEMBL31725319 | 0.85 | LMNA (0.46) | MEN1USP2POLBKMT2AGAPDH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2906579-B1 | 2'-CHLORO NUCLEOSIDE ANALOGS FOR HCV INFECTION | IDENIX PHARMACEUTICALS LLC (US) | 2018-04-18 | — | — | EP | disclosed |
| WO-2013009735-A1 | 5'-SUBSTITUTED NUCLEOSIDE DERIVATIVES AND METHODS OF USE THEREOF FOR THE TREATMENT OF VIRAL DISEASES | MERCK SHARP & DOHME CORP. (US) | 2013-01-17 | — | — | WO | disclosed |