Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | TGM2 | P21980 | 2/20 | 0.33 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | DRD2 | P14416 | 1/20 | 0.30 |
| ▸ | DRD3 | P35462 | 1/20 | 0.30 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | F13A1 | P00488 | 1/20 | 0.30 |
| ▸ | TGM1 | P22735 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19990678 | 0.76 | TGM2 (0.33) | BCHETGM2APOBEC3GEPHX2F13A1 | |
| SCHEMBL22368477 | 0.76 | TGM2 (0.33) | BCHETGM2APOBEC3GEPHX2F13A1 | |
| SCHEMBL15107121 | 0.68 | DPP8 (0.41) | BCHETGM2EPHX2 | |
| SCHEMBL21362364 | 0.68 | BCHE (0.38) | BCHE | |
| SCHEMBL3662286 | 0.67 | DPP8 (0.45) | EPHX2 | |
| SCHEMBL20009183 | 0.64 | BACE1 (0.36) | EPHX2 | |
| SCHEMBL993500 | 0.64 | TSHR (0.41) | TGM2 | |
| SCHEMBL993504 | 0.64 | TSHR (0.41) | TGM2 | |
| SCHEMBL993502 | 0.64 | TSHR (0.41) | TGM2 | |
| SCHEMBL994656 | 0.63 | TSHR (0.38) | BCHETGM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3698796-A1 | PHARMACEUTICAL COMBINATION OF A TRICYCLIC BETA-LACTAMASE INHIBITOR WITH SPECIFIC BETA-LACTAM ANTIBIOTICS | Novartis AG (CH) | 2020-08-26 | — | — | EP | disclosed |