Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREBBP | Q92793 | 16/20 | 0.62 |
| ▸ | BRD4 | O60885 | 14/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GRM5 | P41594 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22369095 | 0.87 | CREBBP (0.67) | CREBBPBRD4 | |
| SCHEMBL22368638 | 0.86 | CREBBP (0.67) | CREBBPBRD4ALDH1A1 | |
| SCHEMBL17680901 | 0.84 | CREBBP (0.68) | CREBBPBRD4GRM5 | |
| SCHEMBL17680982 | 0.81 | CREBBP (0.64) | CREBBPBRD4ALDH1A1 | |
| SCHEMBL17680894 | 0.81 | CREBBP (0.70) | CREBBPBRD4 | |
| SCHEMBL17680986 | 0.77 | CREBBP (0.39) | CREBBPBRD4 | |
| SCHEMBL17680977 | 0.77 | CREBBP (0.68) | CREBBPBRD4ALDH1A1 | |
| SCHEMBL22369208 | 0.77 | CREBBP (0.71) | CREBBPBRD4 | |
| SCHEMBL17673178 | 0.77 | CREBBP (1.00) | CREBBPBRD4 | |
| SCHEMBL17680686 | 0.76 | CREBBP (0.63) | CREBBPBRD4ALDH1A1GRM5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3204360-B1 | THERAPEUTIC COMPOUNDS AND USES THEREOF | GENENTECH INC (US) | 2020-08-26 | — | — | EP | disclosed |