SCHEMBL22369602

SCHEMBL22369602

CC(C)C(C)Nc1ccc(-c2ccccc2)cc1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MMP8 P22894 1/20 0.48
MMP14 P50281 1/20 0.48
CA14 Q9ULX7 1/20 0.48
TDP1 Q9NUW8 2/20 0.48
ALDH1A1 P00352 5/20 0.47
CYP3A4 P08684 2/20 0.47
ALOX15 P16050 2/20 0.47
TSHR P16473 2/20 0.47
ALOX12 P18054 2/20 0.47
HSD17B10 Q99714 2/20 0.47
LMNA P02545 2/20 0.47
THRB P10828 1/20 0.47
RECQL P46063 1/20 0.47
ATM Q13315 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47
TAAR1 Q96RJ0 1/20 0.46
PLK1 P53350 1/20 0.46
SMN1; SMN2 Q16637 1/20 0.42
MAPK1 P28482 2/20 0.40
HIF1A Q16665 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21710835 1.00 MMP8 (0.48) MMP8MMP14CA14TDP1ALDH1A1
SCHEMBL22502960 0.86 TDP1 (0.64) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL2255556 0.86 TDP1 (0.64) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL809564 0.83 ALDH1A1 (0.69) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL632028 0.82 TDP1 (0.73) MMP8MMP14CA14TDP1ALDH1A1
SCHEMBL841689 0.76 TDP1 (0.70) TDP1ALDH1A1CYP3A4ALOX15TSHR
SCHEMBL21704895 0.75 ALDH1A1 (0.72) MMP8MMP14CA14TDP1ALDH1A1
SCHEMBL20146569 0.75 ALDH1A1 (0.72) MMP8MMP14CA14TDP1ALDH1A1
SCHEMBL23485010 0.75 CA1 (0.47) MMP8TDP1ALDH1A1CYP3A4ALOX15
SCHEMBL20670400 0.75 CA1 (0.47) MMP8TDP1ALDH1A1CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3699231-A1 NOVEL POLYMER AND ORGANIC LIGHT-EMITTING DEVICE COMPRISING SAME LG CHEM, LTD. (KR) 2020-08-26 EP disclosed