Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.69 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.69 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.69 |
| ▸ | ALOX12 | P18054 | 4/20 | 0.69 |
| ▸ | TSHR | P16473 | 4/20 | 0.69 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.69 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.69 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.69 |
| ▸ | LMNA | P02545 | 2/20 | 0.69 |
| ▸ | THRB | P10828 | 1/20 | 0.69 |
| ▸ | RECQL | P46063 | 1/20 | 0.69 |
| ▸ | ATM | Q13315 | 1/20 | 0.69 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.56 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.56 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.56 |
| ▸ | HTR2B | P41595 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | MAPT | P10636 | 5/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19018345 | 0.91 | ALDH1A1 (0.75) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL2255556 | 0.91 | TDP1 (0.64) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL22502960 | 0.91 | TDP1 (0.64) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL22369602 | 0.83 | MMP8 (0.48) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL21710835 | 0.83 | MMP8 (0.48) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL38820 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL841689 | 0.81 | TDP1 (0.70) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL1061053 | 0.80 | ALDH1A1 (0.60) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| SCHEMBL29748930 | 0.80 | ALDH1A1 (0.66) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR | |
| N,N'-Diphenyl-P-Phenylenediamine SCHEMBL10454791 | 0.80 | ALDH1A1 (0.95) | ALDH1A1HSD17B10CYP3A4ALOX12TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8062551-B2 | Antiozonant blends | CHEMTURA CORPORATION (US) | 2011-11-22 | — | — | US | claimed |
| EP-2013273-B1 | ANTIOZONANT BLENDS | CHEMTURA CORP (US) | 2011-11-16 | — | — | EP | claimed |
| WO-2011130994-A1 | MULTI-USER CHANNEL ESTIMATION METHOD AND DEVICE | 中兴通讯股份有限公司 (CN) | 2011-10-27 | — | — | WO | claimed |
| EP-1976821-B1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORP (US) | 2011-05-25 | — | — | EP | claimed |
| EP-2013273-A1 | ANTIOZONANT BLENDS | CHEMTURA CORPORATION (US) | 2009-01-14 | — | — | EP | claimed |
| US-7361788-B2 | Direct alkylation of N-alkyl-N′-phenyl-p-phenylenediamine | CHEMTURA CORPORATION (US) | 2008-04-22 | — | — | US | claimed |
| WO-2007130262-A1 | ANTIOZONANT BLENDS | CHEMTURA CORPORATION (US) | 2007-11-15 | — | — | WO | claimed |
| US-20070260000-A1 | Antiozonant blends | ADDIVANT USA, LLC | 2007-11-08 | — | — | US | claimed |
| US-20070173668-A1 | Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine | LANXESS SOLUTIONS US INC. | 2007-07-26 | — | — | US | claimed |
| US-8062551-B2 | Antiozonant blends | CHEMTURA CORPORATION (US) | 2011-11-22 | — | — | US | disclosed |
| EP-2013273-B1 | ANTIOZONANT BLENDS | CHEMTURA CORP (US) | 2011-11-16 | — | — | EP | disclosed |
| WO-2011130994-A1 | MULTI-USER CHANNEL ESTIMATION METHOD AND DEVICE | 中兴通讯股份有限公司 (CN) | 2011-10-27 | — | — | WO | disclosed |
| EP-1976821-B1 | DIRECT ALKYLATION OF N-ALKYL-N'-PHENYL-P-PHENYLENEDIAMINE | CHEMTURA CORP (US) | 2011-05-25 | — | — | EP | disclosed |
| EP-2013273-A1 | ANTIOZONANT BLENDS | CHEMTURA CORPORATION (US) | 2009-01-14 | — | — | EP | disclosed |
| US-5371289-A | Preparation of N-substituted-N'-phenyl p-phenylenediamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-12-06 | — | — | US | disclosed |
| EP-0617004-A1 | Preparation of N-substituted-N'-phenyl-P-phenylenediamines | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1994-09-28 | — | — | EP | disclosed |
| EP-0446554-B1 | PREPARATION OF A N-SUBSTITUTED PHENYLENEDIAMINE | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1993-10-13 | — | — | EP | disclosed |
| US-5068439-A | Chemical intermediates for dyes, drugs, agricultural products and as antoxidants or stabilizers for rubbers | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-11-26 | — | — | US | disclosed |
| EP-0446554-A1 | Preparation of a N-substituted phenylenediamine | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1991-09-18 | — | — | EP | disclosed |
| US-4968843-A | FROM 4-HYDROXYDIPHENYLAMINE; EXCELLENT YIELDS OF HIGH PURITY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1990-11-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070173668-A1 | Direct alkylation of N-alkyl-N'-phenyl-p-phenylenediamine | PNMT, AAAS, PNN | ALDH1A1 663/4885HSD17B10 2077/4885CYP3A4 279/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.