Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.39 |
| ▸ | BAZ2A | Q9UIF9 | 1/20 | 0.39 |
| ▸ | CSF1R | P07333 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1160193 | 0.82 | MEN1 (0.50) | BAZ2BBAZ2ACSF1RMEN1KMT2A | |
| SCHEMBL1299290 | 0.81 | MAPT (0.53) | MEN1KMT2AMAPTNPC1SMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL2237158 | 0.79 | MAPT (0.52) | MEN1KMT2AMAPTNPC1SMN1; SMN2 | |
| SCHEMBL1185764 | 0.75 | NR3C2 (0.42) | CSF1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL20640075 | 0.72 | ALDH1A1 (0.45) | KMT2AMAPTALDH1A1NPC1SMN1; SMN2 | |
| SCHEMBL1663200 | 0.72 | CREBBP (0.54) | CSF1RMEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL1073975 | 0.71 | ALDH1A1 (0.47) | CSF1RMEN1KMT2AALDH1A1GLA | |
| SCHEMBL18414587 | 0.71 | ALDH1A1 (0.41) | CSF1RMEN1KMT2AMAPTALDH1A1 | |
| Water SCHEMBL1662781 | 0.70 | ALDH1A1 (0.46) | CSF1RMEN1KMT2AALDH1A1GLA | |
| SCHEMBL27539694 | 0.70 | ALDH1A1 (0.43) | MEN1KMT2AMAPTALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011088045-A1 | AURORA KINASE COMPOUNDS AND METHODS OF THEIR USE | AMBIT BIOSCIENCES CORPORATION (US) | 2011-07-21 | — | — | WO | disclosed |