Bis(Pyrrolidinylthiocarbonyl)Disulfide

Bis(Pyrrolidinylthiocarbonyl)Disulfide

SCHEMBL2237172

S=C(SSC(=S)N1CCCC1)N1CCCC1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGLL Q99685 9/20 1.00
FBP1 P09467 2/20 1.00
KDM4A O75164 1/20 1.00
PHGDH O43175 7/20 0.94
ALDH1A1 P00352 5/20 0.94
ALDH2 P05091 2/20 0.94
PIN1 Q13526 1/20 0.65
PDK1 Q15118 4/20 0.62
PDK2 Q15119 2/20 0.62
PDK3 Q15120 2/20 0.62
FAAH O00519 2/20 0.59
HTT P42858 1/20 0.52
MAPT P10636 2/20 0.50
HPGD P15428 2/20 0.50
KDM4E B2RXH2 1/20 0.50
TP53 P04637 1/20 0.50
CYP1A2 P05177 1/20 0.50
CYP3A4 P08684 1/20 0.50
CYP2D6 P10635 1/20 0.50
CYP2C9 P11712 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Bis(Piperidinylthiocarbonyl)Disulfide SCHEMBL139465 0.97 MGLL (1.00) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL3271164 0.97 MGLL (1.00) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL14340049 0.94 MGLL (0.88) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL13668385 0.88 MGLL (0.79) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL11811976 0.87 MGLL (0.77) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL22910 0.86 MGLL (0.80) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL10976857 0.86 MGLL (0.80) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL11820140 0.84 MGLL (0.71) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL11825600 0.84 MGLL (0.71) MGLLFBP1KDM4APHGDHALDH1A1
SCHEMBL10887385 0.84 MGLL (0.76) MGLLFBP1KDM4APHGDHALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250163482-A1 NOVEL SYNTHETIC PROMOTER, AND METHOD FOR PRODUCING DAPTOMYCIN USING SAME KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP (KR) 2025-05-22 US claimed
CN-118978904-A CO based on polybasic acid2Heterogeneous supermolecule inclusion synergistic system for oil reservoir flooding, and preparation method and application thereof 中国石油大学(华东) 2024-11-19 CN claimed
CN-118862232-A Self-resetting structure earthquake resistance analysis method based on ABAQUS platform 重庆第二师范学院 2024-10-29 CN claimed
CN-116970544-A Actinomycete daptomycin gene cluster in-situ double-report strain and application thereof 浙江大学 2023-10-31 CN claimed
WO-2023158052-A1 NOVEL SYNTHETIC PROMOTER, AND METHOD FOR PRODUCING DAPTOMYCIN USING SAME 건국대학교 산학협력단 2023-08-24 WO claimed
CN-111892613-B Inorganic-organic hybrid crystal material and synthesis method and application thereof 福建江夏学院 2023-07-21 CN claimed
EP-4662319-A2 PERSONALIZED CRISPR PROFILING FOR CANCER Integrate Bioscience LLC (US) 2025-12-17 EP disclosed
US-20250163482-A1 NOVEL SYNTHETIC PROMOTER, AND METHOD FOR PRODUCING DAPTOMYCIN USING SAME KONKUK UNIVERSITY INDUSTRIAL COOPERATION CORP (KR) 2025-05-22 US disclosed
EP-3877459-B1 POLYMER NETWORK FORMING SILANE COMPOSITIONS MOMENTIVE PERFORMANCE MAT INC (US) 2025-01-22 EP disclosed
EP-4489575-A1 PHYTOSANITARY COMPOSITION AND USE THEREOF De Sangosse (FR) 2025-01-15 EP disclosed
CN-118978904-A CO based on polybasic acid2Heterogeneous supermolecule inclusion synergistic system for oil reservoir flooding, and preparation method and application thereof 中国石油大学(华东) 2024-11-19 CN disclosed
CN-118862232-A Self-resetting structure earthquake resistance analysis method based on ABAQUS platform 重庆第二师范学院 2024-10-29 CN disclosed
EP-4157934-B1 VULCANISABLE COMPOSITION FOR FORMING A NITROSAMINE FREE SULPHUR MODIFIED POLYCHLOROPRENE VULCANISATE ARLANXEO DEUTSCHLAND GMBH (DE) 2024-10-09 EP disclosed
EP-3416653-B1 METHOD AND SYSTEM FOR EARLY RISK ASSESSMENT OF PRETERM DELIVERY OUTCOME TATA CONSULTANCY SERVICES LTD (IN) 2022-05-25 EP disclosed
US-11267955-B2 Polymer network forming silane compositions MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-03-08 US disclosed
CN-109384702-B Preparation method of N-dithiocarbamate indole compound 温州医科大学 2020-08-25 CN disclosed
WO-2011097218-A1 ANTI-CANCER THERAPEUTIC AGENTS WAYNE STATE UNIVERSITY (US) 2011-08-11 WO disclosed
WO-2011030108-A1 JMJD2 DEMETHYLASE INHIBITORS ISIS INNOVATION LIMITED (GB) 2011-03-17 WO disclosed
US-4468526-A Process for the preparation of thiuram disulfides AKZONA INCORPORATED (US) 1984-08-28 US disclosed
US-4459424-A SECONDARY AMINE, CARBON DISULFIDE, METAL CONTAINING CATALYST AKZONA INCORPORATED (US) 1984-07-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11267955-B2 Polymer network forming silane compositions TSN, RIF1, TRHDE MGLL 3316/4885FBP1 2153/4885KDM4A 2462/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.