SCHEMBL2237274

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL2236630	0.89	SMN1; SMN2 (0.38)	MAPK14USP2CYP1A2CYP3A4TSHR
	SCHEMBL2234735	0.86	HTT (0.39)	MAPK14USP2CYP1A2CYP3A4TSHR
	SCHEMBL2234302	0.85	JAK2 (0.36)	USP2CYP1A2CYP3A4TSHRALDH1A1
	SCHEMBL11920292	0.78	CDK1 (0.38)	CDK1GRM1
	SCHEMBL2234500	0.77	GSR (0.38)	MAPK14USP2CYP1A2CYP3A4TSHR
	SCHEMBL2234654	0.76	MET (0.41)	MAPK14F2RL3MCHR1MAOAMAOB
	SCHEMBL2234234	0.76	MAOA (0.38)	MAPK14USP2CYP1A2CYP3A4TSHR
	SCHEMBL2237875	0.76	MAOA (0.38)	MAPK14USP2CYP1A2CYP3A4TSHR
	SCHEMBL11920291	0.76	CDK1 (0.37)	CDK1GRM1
	SCHEMBL2235619	0.76	MAOA (0.38)	MAPK14USP2CYP1A2CYP3A4TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.