SCHEMBL2237366

SCHEMBL2237366

CCCCCCCCC(CCCCCCCC)CCCc1[nH]nnc1N

nearest known ligand 0.35

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.35
ALDH1A1 P00352 1/20 0.33
HCAR2 Q8TDS4 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28089660 0.85 ALDH1A1 (0.39) LMNAALDH1A1HCAR2
SCHEMBL4788302 0.69 ALDH1A1 (0.41) ALDH1A1
SCHEMBL20746187 0.66 LMNA (0.68) LMNAALDH1A1
SCHEMBL20746409 0.66 LMNA (0.68) LMNAALDH1A1
SCHEMBL20746348 0.66 LMNA (0.68) LMNAALDH1A1
SCHEMBL20746351 0.66 LMNA (0.68) LMNAALDH1A1
SCHEMBL25125871 0.66 LMNA (0.68) LMNAALDH1A1
SCHEMBL20746400 0.66 LMNA (0.68) LMNAALDH1A1
SCHEMBL20746363 0.66 LMNA (0.68) LMNAALDH1A1
SCHEMBL20740310 0.66 LMNA (0.68) LMNAALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2451434-A2 ACTIVE-INGREDIENT COMBINATION FOR TREATING MATURE SKIN II Henkel AG & Co. KGaA (DE) 2012-05-16 EP disclosed
EP-2346487-A2 ACTIVE INGREDIENT COMBINATION FOR THE TREATMENT OF MATURE SKIN I Henkel AG & Co. KGaA (DE) 2011-07-27 EP disclosed
WO-2010049011-A2 ACTIVE-INGREDIENT COMBINATION FOR TREATING MATURE SKIN II HENKEL AG & CO. KGAA (DE) 2010-05-06 WO disclosed
WO-2010049457-A2 ACTIVE INGREDIENT COMBINATION FOR THE TREATMENT OF MATURE SKIN I HENKEL AG & CO. KGAA (DE) 2010-05-06 WO disclosed
EP-2180876-A2 STABILISED PICKERING EMULSION Henkel AG & Co. KGaA (DE) 2010-05-05 EP disclosed
WO-2009027538-A2 STABILISED PICKERING EMULSION HENKEL AG & CO. KGAA (DE) 2009-03-05 WO disclosed
EP-2023888-A2 QUICK-DRYING COSMETIC EMULSIONS FOR ROLL-ON APPLICATION Henkel AG & Co. KGaA (DE) 2009-02-18 EP disclosed
WO-2007124889-A2 QUICK-DRYING COSMETIC EMULSIONS FOR ROLL-ON APPLICATION HENKEL AG & CO. KGAA (DE) 2007-11-08 WO disclosed
EP-1725296-A1 RETINOID-CONTAINING PREPARATIONS BASF AKTIENGESELLSCHAFT (DE) 2006-11-29 EP disclosed
WO-2005070373-A1 RETINOID-CONTAINING PREPARATIONS BASF AKTIENGESELLSCHAFT (DE) 2005-08-04 WO disclosed