Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.35 |
| ▸ | PI4KA | P42356 | 1/20 | 0.35 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.35 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.35 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | TLR7 | Q9NYK1 | 2/20 | 0.32 |
| ▸ | HPGD | P15428 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7158489 | 0.98 | ALDH1A1 (0.42) | ALDH1A1HCAR2PI4KAPI4K2BPI4K2A | |
| SCHEMBL9632172 | 0.88 | EPHX2 (0.40) | ALDH1A1KDM4EMAPT | |
| SCHEMBL5017623 | 0.85 | — | — | |
| SCHEMBL2237366 | 0.85 | LMNA (0.35) | ALDH1A1HCAR2LMNA | |
| SCHEMBL4788302 | 0.78 | ALDH1A1 (0.41) | ALDH1A1KDM4E | |
| SCHEMBL9750315 | 0.78 | HCAR2 (0.36) | ALDH1A1HCAR2TLR8MAPTTLR7 | |
| SCHEMBL3722892 | 0.76 | — | — | |
| SCHEMBL19501783 | 0.76 | HCAR2 (0.38) | ALDH1A1HCAR2MAPTHPGDPKM | |
| SCHEMBL11318964 | 0.76 | MEN1 (0.40) | ALDH1A1HCAR2MAPTHPGDLMNA | |
| SCHEMBL7855161 | 0.76 | HCAR2 (0.35) | ALDH1A1HCAR2MAPTHPGDPKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106177984-A | Anti-mesothelin immunoconjugates and application thereof | 拜耳知识产权有限责任公司 | 2016-12-07 | — | — | CN | disclosed |
| CN-102458477-B | Anti-mesothelin immunoconjugates and uses thereof | 拜耳知识产权有限责任公司 | 2016-08-24 | — | — | CN | disclosed |