SCHEMBL2237386

SCHEMBL2237386

O=C1OC(=O)C2CCCCCC(C3=CCCCCCC3)=C12

nearest known ligand 0.35

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.35
CYP3A4 P08684 1/20 0.35
ELANE P08246 1/20 0.35
TYMP P19971 1/20 0.33
FFAR2 O15552 1/20 0.33
HDAC1 Q13547 1/20 0.31
HDAC2 Q92769 1/20 0.31
TDP1 Q9NUW8 1/20 0.31
SMURF1 Q9HCE7 1/20 0.30
CSF1R P07333 1/20 0.30
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2237383 1.00 ALDH1A1 (0.35) ALDH1A1CYP3A4ELANETYMPFFAR2
SCHEMBL2238959 1.00 ALDH1A1 (0.35) ALDH1A1CYP3A4ELANETYMPFFAR2
SCHEMBL2786110 0.75 TYMP (0.35) ALDH1A1CYP3A4ELANETYMPFFAR2
SCHEMBL2236537 0.74 KMT2A (0.32)
SCHEMBL10884031 0.68 ALDH1A1 (0.42) ALDH1A1CYP3A4ELANETYMPHDAC1
SCHEMBL5075378 0.66 HDAC1 (0.33) HDAC1HDAC2
SCHEMBL20574040 0.66 HDAC1 (0.33) HDAC1HDAC2
SCHEMBL2241169 0.65 MAPT (0.33)
SCHEMBL2356347 0.65 MAPT (0.33)
SCHEMBL901386 0.65 MAPT (0.33)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115996996-A Silicone elastomer composition 美国陶氏有机硅公司 2023-04-21 CN disclosed
CN-114206992-A Anhydride and aromatic functionalized polyorganosiloxanes 美国陶氏有机硅公司 2022-03-18 CN disclosed
US-9770442-B2 Self-assembling amphiphilic polymers as anti-cancer agents ALLEXCEL INC. (US) 2017-09-26 US disclosed
EP-2167103-B1 SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTICANCER AGENTS ALLEXCEL INC (US) 2017-03-01 EP disclosed
EP-2120974-B1 SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS ALLEXCEL INC (US) 2017-03-01 EP disclosed
CN-105561324-A Self-assembly amphiphilic polymer used as anticancer agent ALLEXCEL INC 2016-05-11 CN disclosed
CN-101795695-B Self-assembling amphiphilic polymers as anticancer agents ALLEXCEL, INC. (US) 2016-01-06 CN disclosed
EP-1979407-B1 SOLUBILIZATION AND TARGETED DELIVERY OF DRUGS WITH SELF-ASSEMBLING AMPHIPHILIC POLYMERS ALLEXCEL INC (US) 2014-08-06 EP disclosed
US-8173764-B2 Solubilization and targeted delivery of drugs with self-assembling amphiphilic polymers ALLEXCEL INC. (US) 2012-05-08 US disclosed
US-7988748-B2 Additive as component of mineral oil compositions LEUNA POLYMER GMBH (DE) 2011-08-02 US disclosed
EP-2120974-A1 SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS Allexcel, Inc. (US) 2009-11-25 EP disclosed
WO-2009011702-A1 SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTICANCER AGENTS ALLEXCEL, INC. (US) 2009-01-22 WO disclosed
EP-1979407-A1 SOLUBILIZATION AND TARGETED DELIVERY OF DRUGS WITH SELF-ASSEMBLING AMPHIPHILIC POLYMERS Allexcel, Inc. (US) 2008-10-15 EP disclosed
WO-2008091246-A1 SELF-ASSEMBLING AMPHIPHILIC POLYMERS AS ANTIVIRAL AGENTS ALLEXCEL, INC. (US) 2008-07-31 WO disclosed
US-20070219100-A1 Additive Mixture As Component Of A Mineral Oil Composition TAEUBERT HILTRUD 2007-09-20 US disclosed
US-20070180761-A1 Additive as component of mineral oil compositions LEUNA POLYMER GMBH (DE) 2007-08-09 US disclosed
WO-2007084126-A1 SOLUBILIZATION AND TARGETED DELIVERY OF DRUGS WITH SELF-ASSEMBLING AMPHIPHILIC POLYMERS ALLEXCEL, INC. (US) 2007-07-26 WO disclosed
US-20070130821-A1 Additive mixture as component of mineral oil compositions TAEUBERT HILTRUD 2007-06-14 US disclosed
US-6818726-B2 FOR INTERMEDIATES AND MOLDED MATERIALS WITH IMPROVED TOUGHNESS AND HIGH FLAME RESISTANCE AND STRENGTH AGROLINZ MELAMIN GMBH (AT) 2004-11-16 US disclosed
US-20030045667-A1 Polymers made from triazine derivatives AGROLINZ MELAMIN GMBH (AT) 2003-03-06 US disclosed