Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 3/20 | 0.42 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | SHBG | P04278 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | ESR1 | P03372 | 2/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.36 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11173027 | 0.80 | ALOX15 (0.40) | ALOX15ALOX12MCL1PKMMAPK1 | |
| SCHEMBL11647946 | 0.79 | ALOX5 (0.50) | ALOX15MCL1TP53TRPV1KDM4E | |
| SCHEMBL30309307 | 0.78 | MCL1 (0.48) | ALOX15ALOX12MCL1PKMMAPK1 | |
| SCHEMBL4092415 | 0.78 | MCL1 (0.48) | ALOX15ALOX12MCL1PKMMAPK1 | |
| SCHEMBL9231605 | 0.76 | KDM4E (0.50) | ALOX15ALOX12MCL1PKMMAPK1 | |
| SCHEMBL1176482 | 0.76 | CYP2D6 (0.50) | ALOX15ALOX12MCL1PKMMAPK1 | |
| SCHEMBL30485784 | 0.76 | CYP2D6 (0.50) | ALOX15ALOX12MCL1PKMMAPK1 | |
| SCHEMBL14395025 | 0.76 | MCL1 (0.47) | ALOX15ALOX12MCL1PKMMAPK1 | |
| SCHEMBL1245168 | 0.76 | CYP1A2 (0.57) | ALOX15ALOX12PKMMAPK1CYP2D6 | |
| SCHEMBL19621167 | 0.75 | ALDH1A1 (0.38) | ALOX15ALOX12MCL1PKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 188 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10428216-B2 | Golf ball incorporating a mixture of a thermoset and/or thermoplastic composition and a plurality of conductive nanoshelled structures | ACUSHNET COMPANY (US) | 2019-10-01 | — | — | US | disclosed |
| US-20190192922-A1 | GOLF BALL COMPRISING MEDIUM HARDNESS GRADIENT CORE | ACUSHNET COMPANY (US) | 2019-06-27 | — | — | US | disclosed |
| US-10252115-B2 | Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer | ACUSHNET COMPANY (US) | 2019-04-09 | — | — | US | disclosed |
| US-10220263-B2 | Golf balls comprising medium hardness gradient core | ACUSHNET COMPANY (US) | 2019-03-05 | — | — | US | disclosed |
| US-10130848-B2 | Golf ball multilayer core having a gradient quotient | ACUSHNET COMPANY (US) | 2018-11-20 | — | — | US | disclosed |
| US-20180318654-A1 | GOLF BALL INCORPORATING POSITIVE HARDNESS GRADIENT THERMOSET POLYURETHANE OUTER COVER LAYER | ACUSHNET COMPANY (US) | 2018-11-08 | — | — | US | disclosed |
| US-10112081-B2 | Golf ball incorporating positive hardness gradient thermoset polyurethane outer cover layer | ACUSHNET COMPANY (US) | 2018-10-30 | — | — | US | disclosed |
| US-10035046-B2 | Multilayer core golf ball having hardness gradient within and between each core layer | ACUSHNET COMPANY (US) | 2018-07-31 | — | — | US | disclosed |
| US-10029151-B2 | Multi-layer cover golf ball having a high acid casing layer | ACUSHNET COMPANY (US) | 2018-07-24 | — | — | US | disclosed |
| US-10029150-B2 | Golf ball having medium positive gradient quotient and low trans content | ACUSHNET COMPANY (US) | 2018-07-24 | — | — | US | disclosed |
| US-20090011863-A1 | Negative Hardness Gradient Inner Core for Dual Core Golf Ball | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-08 | — | — | US | disclosed |
| US-20090008832-A1 | Negative Hardness Gradient Core Produced from a Low, Temperature-Based Cure Cycle Index | ACUSHNET COMPANY | 2009-01-08 | — | — | US | disclosed |
| US-20090011855-A1 | Golf Ball Core with Soft Outer Transition Volume and Negative Hardness Gradient | ACUSHNET COMPANY | 2009-01-08 | — | — | US | disclosed |
| US-20090011867-A1 | Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Outer Core Layer | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-08 | — | — | US | disclosed |
| US-20090011866-A1 | Multi-Layer Core Golf Ball Having Opposing Hardness Gradient with Steep Gradient Inner Core Layer | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2009-01-08 | — | — | US | disclosed |
| US-7429221-B1 | Negative hardness gradient outer core layer for dual core golf ball | ACUSHNET COMPANY (US) | 2008-09-30 | — | — | US | disclosed |
| US-7410429-B1 | Negative hardness gradient inner core for dual core golf ball | ACUSHNET COMPANY (US) | 2008-08-12 | — | — | US | disclosed |
| US-20080153629-A1 | Thick Outer Cover Layer Golf Ball | ACUSHNET COMPANY | 2008-06-26 | — | — | US | disclosed |
| US-20080146380-A1 | Thick Outer Cover Layer Golf Ball | ACUSHNET COMPANY | 2008-06-19 | — | — | US | disclosed |
| US-20080146378-A1 | Thick Inner Cover Multi-layer Golf Ball | JPMORGAN CHASE BANK, N.A., AS SUCCESSOR ADMINISTRATIVE AGENT | 2008-06-19 | — | — | US | disclosed |