Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.38 |
| ▸ | DDB1 | Q16531 | 12/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21536712 | 0.93 | CRBN (0.39) | CRBNDDB1GAAPOLBKMT2A | |
| SCHEMBL21934559 | 0.83 | NPC1 (0.35) | CRBN | |
| SCHEMBL19541966 | 0.83 | CRBN (0.39) | CRBNDDB1GAAPOLBKMT2A | |
| SCHEMBL19558173 | 0.80 | CRBN (0.40) | CRBNDDB1GAAPOLBKMT2A | |
| SCHEMBL17517847 | 0.75 | DDB1 (0.42) | CRBNDDB1 | |
| SCHEMBL22024311 | 0.75 | CRBN (0.31) | CRBN | |
| SCHEMBL24943449 | 0.72 | ALDH1A1 (0.39) | CRBNKMT2A | |
| SCHEMBL18515841 | 0.72 | MAP3K14 (0.39) | CRBN | |
| SCHEMBL22024310 | 0.70 | CRBN (0.33) | CRBN | |
| SCHEMBL21533866 | 0.69 | NPC1 (0.36) | CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200270207-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200270207-A1 | DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | DUT, TYMP, DPYD | CRBN 3664/4885DDB1 117/4885GAA 346/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.