SCHEMBL22024310

SCHEMBL22024310

CCCC(C)(CCC)C1CCC(=O)N1

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.33
LMNA P02545 1/20 0.32
CCR2 P41597 1/20 0.31
ALDH1A1 P00352 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22024311 0.93 CRBN (0.31) CRBNLMNACCR2
SCHEMBL22023888 0.87 CRBN (0.32) CRBNLMNACCR2
SCHEMBL21191815 0.86 CRBN (0.35) CRBNCCR2ALDH1A1
SCHEMBL26653485 0.86 CCR2 (0.36) CRBNCCR2ALDH1A1
SCHEMBL22023871 0.84 CCR2 (0.36) CRBNCCR2ALDH1A1
SCHEMBL14415910 0.78 LMNA (0.33) CRBNLMNAALDH1A1SMN1; SMN2
SCHEMBL21191593 0.78 CCR2 (0.36) CRBNCCR2ALDH1A1
SCHEMBL7946755 0.77 ALDH1A1 (0.34) CRBNLMNAALDH1A1SMN1; SMN2
SCHEMBL11917928 0.77 ALDH1A1 (0.34) CRBNLMNAALDH1A1SMN1; SMN2
SCHEMBL14916972 0.77 ALDH1A1 (0.34) CRBNLMNAALDH1A1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11198693-B2 Functionalized heterocycles as antiviral agents ENANTA PHARMACEUTICALS, INC. (US) 2021-12-14 US disclosed
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS ENANTA PHARMACEUTICALS, INC. 2020-05-28 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11198693-B2 Functionalized heterocycles as antiviral agents HCCS, HAVCR2, HDGF CRBN 3501/4885LMNA 2656/4885CCR2 521/4885
US-20200165249-A1 FUNCTIONALIZED HETEROCYCLES AS ANTIVIRAL AGENTS HCCS, HAVCR2, HDGF CRBN 3501/4885LMNA 2656/4885CCR2 521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.