Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3CA | P42336 | 2/20 | 0.44 |
| ▸ | MTOR | P42345 | 2/20 | 0.44 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.43 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.43 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | GPR119 | Q8TDV5 | 5/20 | 0.41 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.38 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.38 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.37 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.37 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.36 |
| ▸ | EGLN2 | Q96KS0 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20184050 | 0.90 | PIK3CA (0.44) | PIK3CAMTORHTR2AHTR2CGPR119 | |
| SCHEMBL21055130 | 0.82 | ESR2 (0.53) | PIK3CAMTORGPR119NR1H2 | |
| SCHEMBL15187773 | 0.82 | PIK3CA (0.47) | PIK3CAMTORHTR2AHTR2CHTR2B | |
| SCHEMBL18786921 | 0.81 | NR1H2 (0.54) | PIK3CAMTORGPR119NR1H2 | |
| SCHEMBL29363628 | 0.81 | PIK3CA (0.46) | PIK3CAMTORNR1H2 | |
| SCHEMBL1500153 | 0.81 | PIK3CA (0.46) | PIK3CAMTORNR1H2 | |
| SCHEMBL13827347 | 0.80 | PIK3CA (0.46) | PIK3CAMTORHTR2AHTR2CHTR2B | |
| SCHEMBL16790464 | 0.79 | GPR119 (0.35) | PIK3CAMTORGPR119DRD2AR | |
| SCHEMBL30681316 | 0.79 | PIK3CA (0.45) | PIK3CAMTORHTR2AHTR2CHTR2B | |
| SCHEMBL18961426 | 0.79 | PIK3CA (0.45) | PIK3CAMTORGPR119NR1H2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11285103-B2 | Degradable hydrogel under physiological conditions | HAN JIE (CN) | 2022-03-29 | — | — | US | disclosed |
| US-20200268658-A1 | Degradable hydrogel under physiological conditions | HAN JIE (CN) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268658-A1 | Degradable hydrogel under physiological conditions | PTMS, TRHDE, PHYKPL | PIK3CA 4703/4885MTOR 3082/4885CYP11B1 4681/4885 |
| US-11285103-B2 | Degradable hydrogel under physiological conditions | PTMS, TRHDE, PHYKPL | PIK3CA 4703/4885MTOR 3082/4885CYP11B1 4681/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.