Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | CLK1 | P49759 | 1/20 | 0.41 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.41 |
| ▸ | NR3C2 | P08235 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | CFTR | P13569 | 1/20 | 0.36 |
| ▸ | GOPC | Q9HD26 | 1/20 | 0.36 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | ALPL | P05186 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20968027 | 0.89 | SMN1; SMN2 (0.45) | SMN1; SMN2ALDH1A1HTTCLK1DYRK1A | |
| SCHEMBL20694181 | 0.88 | NR3C2 (0.42) | SMN1; SMN2ALDH1A1HTTNR3C2SLC6A2 | |
| SCHEMBL19954875 | 0.83 | SMN1; SMN2 (0.38) | SMN1; SMN2ALDH1A1HTTCLK1DYRK1A | |
| SCHEMBL18683654 | 0.82 | NR3C2 (0.46) | SMN1; SMN2ALDH1A1HTTNR3C2SLC6A2 | |
| SCHEMBL25135962 | 0.81 | NR3C2 (0.36) | SMN1; SMN2ALDH1A1HTTNR3C2SLC6A2 | |
| SCHEMBL24344055 | 0.79 | NR3C2 (0.43) | SMN1; SMN2ALDH1A1HTTNR3C2SLC6A2 | |
| SCHEMBL18950253 | 0.77 | SLC6A2 (0.42) | SMN1; SMN2ALDH1A1HTTNR3C2SLC6A2 | |
| SCHEMBL22197081 | 0.77 | KCNA5 (0.43) | SMN1; SMN2ALDH1A1HTTNAMPTL3MBTL1 | |
| SCHEMBL21161714 | 0.76 | ALPL (0.39) | SMN1; SMN2ALDH1A1HTTCLK1DYRK1A | |
| SCHEMBL27295384 | 0.75 | SLC6A2 (0.47) | SMN1; SMN2ALDH1A1HTTCLK1DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230303489-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2023-09-28 | — | — | US | disclosed |
| US-11542233-B2 | Compounds, compositions and methods of use | AQUINNAH PHARMACEUTICALS, INC. (US) | 2023-01-03 | — | — | US | disclosed |
| US-20200270211-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | AQUINNAH PHARMACEUTICALS INC (US) | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11542233-B2 | Compounds, compositions and methods of use | FUS, TFEB, CLN6 | SMN1; SMN2 35/4885ALDH1A1 3706/4885HTT 56/4885 |
| US-20200270211-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | FUS, TFEB, CLN6 | SMN1; SMN2 35/4885ALDH1A1 3706/4885HTT 56/4885 |
| US-20230303489-A1 | COMPOUNDS, COMPOSITIONS AND METHODS OF USE | FUS, TFEB, CLN6 | SMN1; SMN2 35/4885ALDH1A1 3706/4885HTT 56/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.