Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 3/20 | 0.33 |
| ▸ | HTR2C | P28335 | 3/20 | 0.33 |
| ▸ | HTR2B | P41595 | 3/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18592218 | 0.76 | DRD2 (0.40) | DRD2HTR2ASIGMAR1 | |
| SCHEMBL18591774 | 0.75 | PRCP (0.42) | DRD2HTR2A | |
| SCHEMBL18591766 | 0.72 | ACACB (0.33) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL23664608 | 0.69 | HRH3 (0.41) | DRD2SIGMAR1 | |
| SCHEMBL22965358 | 0.68 | CARM1 (0.45) | DRD2HTR2ASIGMAR1 | |
| SCHEMBL25053674 | 0.68 | DRD2 (0.44) | DRD2HTR2A | |
| SCHEMBL21965867 | 0.68 | DRD2 (0.46) | DRD2HTR2A | |
| SCHEMBL20133291 | 0.68 | ACACB (0.33) | — | |
| SCHEMBL24920843 | 0.67 | ACACB (0.33) | DRD2HTR2AHTR2CHTR2BSIGMAR1 | |
| SCHEMBL26328562 | 0.66 | ACACB (0.33) | DRD2HTR2AHTR2CHTR2BSIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | DRD2 4841/4885HTR2A 4487/4885HTR2C 4616/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.