Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 12/20 | 0.57 |
| ▸ | CA1 | P00915 | 11/20 | 0.57 |
| ▸ | CA12 | O43570 | 10/20 | 0.57 |
| ▸ | CA9 | Q16790 | 9/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | HTT | P42858 | 1/20 | 0.50 |
| ▸ | SOS1 | Q07889 | 4/20 | 0.49 |
| ▸ | CA7 | P43166 | 4/20 | 0.47 |
| ▸ | CA5A | P35218 | 2/20 | 0.47 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.47 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.47 |
| ▸ | CA3 | P07451 | 1/20 | 0.47 |
| ▸ | CA6 | P23280 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.47 |
| ▸ | CA4 | P22748 | 1/20 | 0.45 |
| ▸ | KIF11 | P52732 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23519059 | 0.83 | PTGS2 (0.47) | CA2CA1CA12CA9PTGS2 | |
| SCHEMBL23519069 | 0.81 | HSD11B1 (0.47) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL23519076 | 0.80 | ELANE (0.54) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL23519068 | 0.80 | CA12 (0.39) | CA2CA1CA12CA9HTT | |
| SCHEMBL1137645 | 0.80 | PTGS2 (0.65) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL9496011 | 0.78 | PTGS2 (0.63) | CA2CA1CA12CA9ALDH1A1 | |
| Ammonia Solution, Strong SCHEMBL29087279 | 0.78 | PTGS2 (0.63) | CA2CA1CA12CA9ALDH1A1 | |
| Hydrochloric Acid SCHEMBL29087408 | 0.78 | PTGS2 (0.63) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL30596352 | 0.78 | PTGS2 (0.63) | CA2CA1CA12CA9ALDH1A1 | |
| SCHEMBL23519065 | 0.77 | EPHX2 (0.55) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | YALE UNIVERSITY | 2020-08-27 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200268897-A1 | Phosphatase Binding Compounds and Methods of Using Same | PPP5C, PPP4C, DUSP26 | CA2 2737/4885CA1 3292/4885CA12 4153/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.