Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 9/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 6/20 | 0.48 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.48 |
| ▸ | FAP | Q12884 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.43 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.43 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | MDH1 | P40925 | 1/20 | 0.42 |
| ▸ | MDH2 | P40926 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12354573 | 0.85 | DPP4 (0.53) | DPP4DPP8DPP9FAPEPHX2 | |
| SCHEMBL2300337 | 0.85 | EPHX2 (0.53) | DPP4DPP8DPP9EPHX2MEN1 | |
| SCHEMBL27974243 | 0.82 | DPP4 (0.50) | DPP4DPP8DPP9FAPEPHX2 | |
| SCHEMBL12735378 | 0.79 | DPP4 (0.56) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL160300 | 0.79 | DPP4 (0.58) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL13287421 | 0.78 | MEN1 (0.55) | DPP8DPP9EPHX2ITGB3ITGA2B | |
| SCHEMBL17057322 | 0.77 | EPHX2 (0.49) | DPP4DPP8DPP9FAPEPHX2 | |
| SCHEMBL10487757 | 0.77 | EPHX2 (0.42) | DPP4DPP8DPP9EPHX2ITGB3 | |
| SCHEMBL16087541 | 0.73 | DPP4 (0.53) | DPP4DPP8DPP9FAPEPHX2 | |
| SCHEMBL16659674 | 0.72 | DPP4 (0.41) | DPP4DPP8DPP9FAPEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101861-A1 | PROCESS FOR PREPARATION OF DPP-IV INHIBITORS | MSN LABORATORIES LIMITED (IN) | 2011-08-25 | — | — | WO | claimed |
| WO-2011101861-A1 | PROCESS FOR PREPARATION OF DPP-IV INHIBITORS | MSN LABORATORIES LIMITED (IN) | 2011-08-25 | — | — | WO | disclosed |
| WO-2011101861-A1 | PROCESS FOR PREPARATION OF DPP-IV INHIBITORS | MSN LABORATORIES LIMITED (IN) | 2011-08-25 | — | — | WO | disclosed |