Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 10/20 | 0.53 |
| ▸ | DPP8 | Q6V1X1 | 5/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.49 |
| ▸ | FAP | Q12884 | 1/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | GLMN | Q92990 | 1/20 | 0.44 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA7 | P43166 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | MDH1 | P40925 | 1/20 | 0.40 |
| ▸ | MDH2 | P40926 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27974243 | 0.87 | DPP4 (0.50) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL2237495 | 0.85 | DPP4 (0.49) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL12735378 | 0.84 | DPP4 (0.56) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL160300 | 0.83 | DPP4 (0.58) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL7438003 | 0.83 | DPP4 (0.53) | DPP4EPHX2CA12CA2CA7 | |
| SCHEMBL17057322 | 0.82 | EPHX2 (0.49) | DPP4DPP8DPP9FAPALDH1A1 | |
| SCHEMBL16087541 | 0.77 | DPP4 (0.53) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL15114218 | 0.76 | GRIN2D (0.47) | DPP4DPP8DPP9FAPALDH1A1 | |
| SCHEMBL2853219 | 0.76 | DPP4 (0.50) | DPP4DPP8DPP9FAPDPP7 | |
| SCHEMBL5608094 | 0.76 | ALDH1A1 (0.47) | DPP4DPP8DPP9DPP7ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101861-A1 | PROCESS FOR PREPARATION OF DPP-IV INHIBITORS | MSN LABORATORIES LIMITED (IN) | 2011-08-25 | — | — | WO | disclosed |