Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | DPP4 | P27487 | 4/20 | 0.47 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.43 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.43 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.42 |
| ▸ | TOP2A | P11388 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2237495 | 0.85 | DPP4 (0.49) | EPHX2MEN1MAPK1KMT2ADPP4 | |
| SCHEMBL10487757 | 0.84 | EPHX2 (0.42) | EPHX2MEN1MAPK1KMT2ADPP4 | |
| SCHEMBL7438003 | 0.82 | DPP4 (0.53) | EPHX2MEN1KMT2ADPP4TOP2A | |
| SCHEMBL7430443 | 0.78 | EPHX2 (0.52) | EPHX2DPP4TOP2A | |
| SCHEMBL5577141 | 0.78 | HSD17B10 (0.45) | EPHX2MEN1MAPK1KMT2ADPP4 | |
| SCHEMBL21244840 | 0.76 | CACNA1H (0.57) | EPHX2MEN1MAPK1KMT2ADPP8 | |
| SCHEMBL14696502 | 0.75 | EPHX2 (0.48) | EPHX2MEN1MAPK1KMT2ACACNA1H | |
| SCHEMBL12735376 | 0.74 | DPP4 (0.56) | EPHX2KMT2ADPP4 | |
| SCHEMBL29632942 | 0.74 | EPHX2 (0.57) | EPHX2MEN1MAPK1KMT2ACACNA1H | |
| SCHEMBL136224 | 0.74 | KMT2A (0.73) | EPHX2MEN1MAPK1KMT2ADPP8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011101861-A1 | PROCESS FOR PREPARATION OF DPP-IV INHIBITORS | MSN LABORATORIES LIMITED (IN) | 2011-08-25 | — | — | WO | disclosed |