SCHEMBL22375223

SCHEMBL22375223

CN(C)C(=O)Sc1cc(Cl)ccc1-c1cc(F)c(-c2ccc(Cl)cc2SC(=O)N(C)C)cc1F

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 2/20 0.43
HTT P42858 1/20 0.43
ALDH1A1 P00352 3/20 0.38
GRIN2B Q13224 1/20 0.36
KMO O15229 2/20 0.36
MEN1 O00255 2/20 0.35
KMT2A Q03164 2/20 0.35
MAPT P10636 1/20 0.35
ALPL P05186 1/20 0.35
CCR2 P41597 2/20 0.34
NPC1 O15118 2/20 0.34
RAB9A P51151 2/20 0.34
POLB P06746 1/20 0.34
APP P05067 2/20 0.33
FSCN1 Q16658 1/20 0.33
AKR1C3 P42330 1/20 0.33
AKR1C2 P52895 1/20 0.33
GRM2 Q14416 1/20 0.33
LMNA P02545 1/20 0.33
UBE2N P61088 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2472875 0.74 SMN1; SMN2 (0.49) HPGDHTTALDH1A1MEN1KMT2A
SCHEMBL5706827 0.71 HTT (0.44) HTTALDH1A1KMT2ACCR2
SCHEMBL13159056 0.71 ABL1 (0.49) HPGDHTTALDH1A1MEN1KMT2A
SCHEMBL2473934 0.71 ABL1 (0.53) HPGDHTTALDH1A1MEN1KMT2A
SCHEMBL17964043 0.69 NCEH1 (0.41) ALDH1A1KMT2AMAPTNPC1RAB9A
SCHEMBL254680 0.67 HPGD (0.55) HPGDHTTALDH1A1MEN1KMT2A
SCHEMBL10891104 0.67 SLC6A4 (0.33) HPGDHTTALDH1A1MEN1KMT2A
SCHEMBL11226102 0.67 MAPT (0.54) HPGDHTTALDH1A1MAPTNPC1
SCHEMBL2472153 0.66 HPGD (0.39) HPGDHTTALDH1A1MEN1KMT2A
SCHEMBL22375221 0.66 HSD17B10 (0.50) HPGDHTTALDH1A1KMOMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200274077-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING APPARATUS SONY CORPORATION (JP) 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200274077-A1 PHOTOELECTRIC CONVERSION ELEMENT AND IMAGING APPARATUS PPOX, JUP, L1CAM HPGD 3953/4885HTT 4831/4885ALDH1A1 2007/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.