SCHEMBL2237562

SCHEMBL2237562

Cc1ccoc1C1=Cc2c(ccc(C)c2-c2cccc(C(C)(C)C)c2)C1

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
TMEM97 Q5BJF2 1/20 0.32
SIGMAR1 Q99720 1/20 0.32
KIF11 P52732 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2384956 0.80 KIF11 (0.32) KIF11
SCHEMBL2235094 0.77 KIF11 (0.37) TMEM97SIGMAR1KIF11
SCHEMBL2381260 0.77
SCHEMBL4625148 0.70 POLB (0.34)
SCHEMBL2236454 0.70 KIF11 (0.39) TMEM97SIGMAR1KIF11
SCHEMBL2236712 0.69
SCHEMBL2236889 0.66 RXRB (0.33)
SCHEMBL2238185 0.65 NQO2 (0.31)
SCHEMBL2235242 0.64
SCHEMBL23566934 0.63 NOTUM (0.46)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2360163-A1 METALLOCENE COMPLEX AND METHOD FOR POLYMERIZING OLEFIN Japan Polypropylene Corporation (JP) 2011-08-24 EP disclosed