Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.38 |
| ▸ | PDE4A | P27815 | 3/20 | 0.36 |
| ▸ | PDE4B | Q07343 | 3/20 | 0.36 |
| ▸ | PDE4C | Q08493 | 3/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 3/20 | 0.36 |
| ▸ | TRPM2 | O94759 | 1/20 | 0.36 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.35 |
| ▸ | SIRT2 | Q8IXJ6 | 2/20 | 0.34 |
| ▸ | NADK | O95544 | 1/20 | 0.34 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.34 |
| ▸ | ADORA2B | P29275 | 2/20 | 0.34 |
| ▸ | RAPGEF3 | O95398 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | HSPA5 | P11021 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2989054 | 0.89 | ADORA3 (0.33) | ADORA3ADORA2APDE4APDE4BPDE4C | |
| SCHEMBL5348155 | 0.86 | CHKA (0.42) | ADORA1 | |
| SCHEMBL8718545 | 0.81 | ADORA3 (0.48) | ADORA3ADORA2ATRPM2SLC28A2NADK | |
| SCHEMBL6390181 | 0.77 | DCK (0.36) | MAPT | |
| SCHEMBL5200171 | 0.77 | POLB (0.40) | LMNAMAPT | |
| SCHEMBL16401776 | 0.76 | TYMP (0.42) | ADORA1 | |
| SCHEMBL6911080 | 0.74 | SLC29A1 (0.44) | ADORA3ADORA1TSHR | |
| SCHEMBL17599855 | 0.74 | NT5E (0.49) | ADORA3ADORA1ADORA2B | |
| SCHEMBL10690523 | 0.74 | ADORA3 (0.50) | ADORA3ADORA1ADORA2BHIF1A | |
| SCHEMBL6710679 | 0.74 | TYMP (0.43) | ADORA3ADORA2ATRPM2ADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8758995-B2 | Solid phase sequencing of biopolymers | SEQUENOM, INC. (US) | 2014-06-24 | — | — | US | disclosed |
| US-20110172111-A1 | SOLID PHASE SEQUENCING OF BIOPOLYMERS | SEQUENOM, INC. (US) | 2011-07-14 | — | — | US | disclosed |
| US-7803529-B1 | Solid phase sequencing of biopolymers | SEQUENOM, INC. (US) | 2010-09-28 | — | — | US | disclosed |
| US-7771929-B2 | Tag library compounds, compositions, kits and methods of use | MONOGRAM BIOSCIENCES, INC. (US) | 2010-08-10 | — | — | US | disclosed |
| US-20060063193-A1 | Solid phase sequencing of double-stranded nucleic acids | TRUSTEES OF BOSTON UNIVERSITY, THE | 2006-03-23 | — | — | US | disclosed |
| US-6991903-B2 | Solid phase sequencing of double-stranded nucleic acids | SEQUENOM, INC. (US) | 2006-01-31 | — | — | US | disclosed |
| US-20050053939-A1 | Methods and compositions for enhancing detection in determinations employing cleavable electrophoretic tag reagents | MONOGRAM BIOSCIENCES, INC. | 2005-03-10 | — | — | US | disclosed |
| US-20040265858-A1 | Sets of generalized target-binding e-tag probes | SINGH SHARAT | 2004-12-30 | — | — | US | disclosed |
| US-20040197815-A1 | Methods for detecting aggregations of proteins | SINGH SHARAT (US) | 2004-10-07 | — | — | US | disclosed |
| US-20040166529-A1 | Sets of generalized target-binding e-tag probes | SINGH SHARAT (US) | 2004-08-26 | — | — | US | disclosed |
| US-20020015954-A1 | Sets of oligonucleotide-binding e-tag probes | MONOGRAM BIOSCIENCES, INC. | 2002-02-07 | — | — | US | disclosed |
| US-20020009737-A1 | Kits employing oligonucleotide-binding e-tag probes | MONOGRAM BIOSCIENCES, INC. | 2002-01-24 | — | — | US | disclosed |
| US-20020001808-A1 | Methods employing oligonucleotide-binding e-tag probes | MONOGRAM BIOSCIENCES, INC. | 2002-01-03 | — | — | US | disclosed |
| US-20010051340-A1 | Kits employing generalized target-binding e-tag probes | MONOGRAM BIOSCIENCES, INC. | 2001-12-13 | — | — | US | disclosed |
| US-6238871-B1 | HIGH SPEED; HIGH THROUGHPUT; NO REQUIRED ELECTROPHORESIS; SANGER SEQUENCING STRATEGY, THEN DETERMINING SEQUENCE BY ALIGNING TERMINATED FRAGMENTS ACCORDING TO MOLECULAR WEIGHT | SEQUENOM, INC. | 2001-05-29 | — | — | US | disclosed |
| US-6225450-B1 | INTACT POSITIVELY CHARGED IONIZED MASS-MODIFIED NUCLEIC ACID MOLECULE | SEQUENOM, INC. | 2001-05-01 | — | — | US | disclosed |
| US-6194144-B1 | GENERATING TWO TERMINATED NUCLEIC ACIDS; DETERMINATION MOLECULAR WEIGHT; CALIBRATION | SEQUENOM, INC. | 2001-02-27 | — | — | US | disclosed |
| WO-1997037041-A9 | DNA SEQUENCING BY MASS SPECTROMETRY | — | 1997-12-31 | — | — | WO | disclosed |
| EP-0679196-A1 | DNA SEQUENCING BY MASS SPECTROMETRY | SEQUENOM, INC. (US) | 1995-11-02 | — | — | EP | disclosed |
| WO-1994016101-A2 | DNA SEQUENCING BY MASS SPECTROMETRY | KOESTER HUBERT (US) | 1994-07-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040197815-A1 | Methods for detecting aggregations of proteins | SNRPE, PEBP1, PHAX | ADORA3 3648/4885ADORA2A 3716/4885PDE4A 3096/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.