SCHEMBL22378265

SCHEMBL22378265

N#Cc1ccc2c(c1)c1cccc(C#N)c1n2-c1ccc(C#N)c(-c2ccc(-c3ccccc3-n3c4ccccc4c4ccccc43)cc2)c1

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
NR3C1 P04150 1/20 0.35
ESR2 Q92731 1/20 0.32
PTGER4 P35408 1/20 0.30
TDP2 O95551 2/20 0.30
KDM1A O60341 1/20 0.30
TNKS2 Q9H2K2 1/20 0.30
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
HPGD P15428 1/20 0.30
MAPK1 P28482 1/20 0.30
SMN1; SMN2 Q16637 1/20 0.30
PPARG P37231 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22379757 1.00 NR3C1 (0.35) NR3C1ESR2PTGER4TDP2KDM1A
SCHEMBL22378267 0.98 NR3C1 (0.36) NR3C1ESR2PTGER4TDP2KDM1A
SCHEMBL22378272 0.98 NR3C1 (0.36) NR3C1ESR2PTGER4TDP2KDM1A
SCHEMBL24831026 0.95 NR3C1 (0.34) NR3C1ALDH1A1LMNAHPGDMAPK1
SCHEMBL22377882 0.95 NR3C1 (0.36) NR3C1ESR2PTGER4TDP2TNKS2
SCHEMBL22379590 0.95 NR3C1 (0.36) NR3C1ESR2PTGER4TDP2TNKS2
SCHEMBL22378767 0.93 NR3C1 (0.37) NR3C1ESR2PTGER4TDP2KDM1A
SCHEMBL22377611 0.93 NR3C1 (0.34) NR3C1ESR2PTGER4KDM1ATNKS2
SCHEMBL22379753 0.93 NR3C1 (0.34) NR3C1ESR2PTGER4KDM1ATNKS2
SCHEMBL22378760 0.93 NR3C1 (0.34) NR3C1ESR2PTGER4KDM1ATNKS2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-24 US disclosed
US-20200274074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200274074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CRY2 NR3C1 1012/4885ESR2 473/4885PTGER4 1068/4885
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CYP1A1, CRY2 NR3C1 1012/4885ESR2 473/4885PTGER4 1068/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.