SCHEMBL22378331

SCHEMBL22378331

N#Cc1ccc2c(c1)c1ccccc1n2-c1cccc(-c2cccc(-c3c(C#N)cccc3-n3c4ccccc4c4ccccc43)c2)c1

nearest known ligand 0.34

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.34
ATM Q13315 1/20 0.34
L3MBTL1 Q9Y468 1/20 0.34
HRH1 P35367 1/20 0.33
HTR6 P50406 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.33
DHFR P00374 1/20 0.33
HIF1A Q16665 1/20 0.33
G6PD P11413 1/20 0.32
TDP2 O95551 1/20 0.31
PTGER4 P35408 2/20 0.31
ALDH1A1 P00352 1/20 0.31
LMNA P02545 1/20 0.31
HPGD P15428 1/20 0.31
MAPK1 P28482 1/20 0.31
RORC P51449 1/20 0.31
ENPP3 O14638 1/20 0.31
MEN1 O00255 1/20 0.31
KMT2A Q03164 1/20 0.31
GRIN1 Q05586 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL26614290 1.00 KDM4E (0.34) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL22378412 1.00 KDM4E (0.34) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL22379108 1.00 KDM4E (0.34) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL21599609 0.98 KDM4E (0.36) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL19755288 0.98 KDM4E (0.36) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL19755284 0.98 KDM4E (0.36) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL21599856 0.98 KDM4E (0.36) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL24830824 0.97 HRH1 (0.32) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL26614287 0.97 HRH1 (0.32) KDM4EATML3MBTL1HRH1HTR6
SCHEMBL22379751 0.96 DHFR (0.33) KDM4EATML3MBTL1HRH1HTR6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-24 US disclosed
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-24 US disclosed
US-20200274074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200274074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CRY2 KDM4E 3290/4885ATM 3429/4885L3MBTL1 1164/4885
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CYP1A1, CRY2 KDM4E 3290/4885ATM 3429/4885L3MBTL1 1164/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.