SCHEMBL22378640

SCHEMBL22378640

N#Cc1c(-c2ccccc2-c2ccccc2-n2c3ccccc3c3ccccc32)cccc1-n1c2ccccc2c2ccccc21

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.40
EGFR P00533 1/20 0.38
SRC P12931 1/20 0.38
MAPT P10636 2/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
ATM Q13315 1/20 0.37
GAA P10253 3/20 0.36
MEN1 O00255 2/20 0.36
KMT2A Q03164 2/20 0.36
CACNA1B Q00975 1/20 0.36
APBA1 Q02410 1/20 0.36
DUSP3 P51452 1/20 0.35
IMPDH2 P12268 1/20 0.34
MAPK1 P28482 2/20 0.34
STAT3 P40763 1/20 0.34
CYP1A2 P05177 2/20 0.33
CYP2C19 P33261 2/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19755252 0.98 ALDH1A1 (0.41) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL22377824 0.97 ALDH1A1 (0.40) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL12679886 0.95 ALDH1A1 (0.41) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL19051994 0.95 ALDH1A1 (0.43) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL22377454 0.92 ALDH1A1 (0.37) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL19755320 0.90 ALDH1A1 (0.38) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL22378582 0.90 SMN1; SMN2 (0.41) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL22379417 0.90 SMN1; SMN2 (0.41) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL17952695 0.89 SMN1; SMN2 (0.44) ALDH1A1EGFRSRCMAPTSMN1; SMN2
SCHEMBL22379414 0.89 PTGER4 (0.34) ALDH1A1SMN1; SMN2HIF1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-24 US disclosed
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same SAMSUNG ELECTRONICS CO., LTD. (KR) 2023-10-24 US disclosed
US-20200274074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME SAMSUNG ELECTRONICS CO., LTD. (KR) 2020-08-27 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200274074-A1 HETEROCYCLIC COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE INCLUDING THE SAME CRY1, CYP1A1, CRY2 ALDH1A1 19/4885EGFR 3815/4885SRC 3999/4885
US-11800797-B2 Heterocyclic compound and organic light-emitting device including the same CRY1, CYP1A1, CRY2 ALDH1A1 19/4885EGFR 3815/4885SRC 3999/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.